Neurol. pro Praxi, 2001; 2: 73-75

Anestezie a nervosvalová onemocnění

doc. MUDr. Otakar Keller, CSc.
Neurologická klinika IPVZ, Fakultní Thomayerova nemocnice Praha

Keywords: anestezie, myorelaxancia, maligní hyperpyrexie, rhabdomyolýza, hypertermie, myopatie.

Published: December 31, 2001  Show citation

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Keller O. Anestezie a nervosvalová onemocnění. Neurol. praxi. 2001;2(2):73-75.

Při anestezii u nemocných se svalovým postižením někdy dochází ke specifickým komplikacím. Tato zkušenost vedla ke studiu vlivů některých narkotik na fyziologii nervosvalového přenosu a fyziologii svalové kontrakce. Narkotika a myorelaxancia ovlivňují membránové děje na svalovém vláknu, zejména v oblasti nervosvalové ploténky. Kromě toho mohou narušit i fyziologický průběh excitačně-kontrakčního spojení, který probíhá v oblasti sarkoplazmatického retikula.

Kritický stav vysoké teploty a svalové ztuhlosti, který vedl často k selhání respiračních funkcí a oběhového systému, byl nazván maligní hyperpyrexií. U některých onemocnění nervů a svalů se však mohou vyskytovat i jiné komplikace.

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