Neurol. pro Praxi, 2003; 2: 63-66

Preventívna liečba migrény

doc. MUDr. h. Vladimír Donáth PhD
Neurologické oddelenie, Nemocnica F.D. Roosevelta, Banská Bystrica

Published: December 31, 2003  Show citation

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Donáth HV. Preventívna liečba migrény. Neurol. praxi. 2003;4(2):63-66.

Migréna je pomerne často sa vyskytujúce chronické ochorenie. Prejavuje sa opakovanými záchvatmi intenzívnych jednostranných, zvyčajne pulzujúcich bolestí hlavy. Moľnosti zvládnu» migrénu sú v aplikácii tak preventívnej liečby ako aj akútnej liečby migrénového záchvatu. Cieµom preventívnej liečby je redukcia počtu, trvania a závaľnosti migrénových záchvatov. Vysoká účinnos» profylaktického účinku sa dokumentovala u betablokátorov, valproátu a amitriptylínu. Stredný stupeň účinnosti sa zaznamenal pri inhibítoroch spätného vychytávania serotonínu (SSRI), blokátoroch kalciových kanálov, topiramátu, gabapentínu, riboflavínu a nesteroidných antireumatikách.

Kµúčové slová

serotonín, 5-HT receptory, migréna, prevencia, terapia migrény.

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