Neurol. praxi. 2008;9(6):356-360
Menstrual migraine is a subtype of migraine without aura. Pure menstrual migraine (PMM) which occurs during menstruation, and menstrually-related migraine (MRM) which can also occur outside menstruation are distinguished. In pathophysiology, a decrease in the oestrogen level by the end of the luteal phase of the cycle as well as an increase in prostaglandin within the first 48 hours of menstruation are thought to play the main role. Acute treatment and prophylaxis of MRM do not differ from the routine treatment. Prophylactic treatment of PMM involves intermittent prophylaxis with nonsteroid anti-inflammatory drugs or frovatriptan, hormonal prophylaxis involves the use of steadily high
or low levels of oestrogens.
Published: January 1, 2009 Show citation