Neurol. praxi. 2010;11(5):320-326

Antiphospholipid syndrome: one of the causes of ischaemic stroke in young age

MUDr.Andrea Bártková
Iktové centrum, Neurologická klinika LF UP a FN Olomouc

Antiphospholipid syndrome (APS) is a rather rare condition with a great variability of clinical signs and many pitfalls in differential diagnosis.

APS is defined by a complex of clinical and laboratory features. The clinical criterion is vascular thrombosis and/or complications

of pregnancy and laboratory evidence involves the presence of antiphospholipid antibodies (APA). In addition to vascular thrombosis,

the most common manifestation of APS is ischaemic stroke. The correct recognition of the fact that neurovascular symptoms are caused

by APS is crucial for the management of the disease and its treatment. Some neurovascular clinical manifestations associated with APS

are presented as brief case reports.

therapy.

Keywords: antiphospholipid syndrome, antiphospholipid antibodies, thrombosis, ischaemic stroke, heart valve lesions, anticoagulant

Published: December 1, 2010  Show citation

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Bártková A. Antiphospholipid syndrome: one of the causes of ischaemic stroke in young age. Neurol. praxi. 2010;11(5):320-326.
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