Neurol. praxi. 2011;12(3):188-190

Epilepsy and metabolic syndrome X

MUDr.Irena Novotná
1. neurologická klinika LF MU a FN u sv. Anny v Brně

Metabolic syndrome is a common disease in all population groups. It is characterized by obesity, hypertension, hyperglycaemia, and

hyperlipidaemia (Tung M Fong, 2004). The aetiology may be determined genetically; however, lifestyle factors play a major role, particularly

excess caloric intake and sedentary lifestyle. The condition may be aggravated by some medications, e. g. antiepileptics, which are

administered on a long-term basis in individuals with epilepsy. Thus, when selecting an antiepileptic drug, the patient's comorbidities

have to be taken into consideration.

Keywords: metabolic syndrome X, epilepsy, antiepileptic drugs, lipid metabolism

Published: June 1, 2011  Show citation

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Novotná I. Epilepsy and metabolic syndrome X. Neurol. praxi. 2011;12(3):188-190.
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References

  1. Arvanikatis Z, Wilson RS, Bienias JL, Evens DA, Bennet DA. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol, 2004; 61: 661-666). Go to original source... Go to PubMed...
  2. den Heier T, Vermeer SE, van Dijk EJ, Prins ND, Koudstaal PJ, Hofman A, Breteler MM. Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI. Diabetologia, 2003; 46: 1604-1610). Go to original source... Go to PubMed...
  3. Erfurth A, Kuhn G. Topiramate Monotherapy in the Maintenace Treatment of Bipolar Disorder: Effects on Mood, Weight and Serum Lipids: Neuropsychobiology 2004: 42.
  4. Franzoni E, Verrotti A, Sarajlija J, Garone C, Matricardi S, Salerno GG, Monti M, Chiarelli F. Topiramate: effects on serum lipids and liporoteine levels in children: European Journal of neurology, 2007. Go to original source... Go to PubMed...
  5. Chengappa R, Chalasani L, Brar J, Parepally H, Houck P, Levine J. Changes in Body Weight and Body mass Index Among Psychiatric Patients Receiving Lithium, Valproate, or Topiramate: An Open - Label, Nonrandomized Chart Review: Clinical Therapeutics: 2002. Go to original source...
  6. Svačina, S. Postgraduál med. 2004; 6: 657.
  7. Tung M Fong. Targeting Metabolic Syndrome: Ashley Publicatoins, 2004. Go to original source...
  8. Wellmer J, Wellmer S, Bauer J. The impact of zonisamide on weight. A clinical study in 103 patients with epilepsy: Acta Neurologica Scandinavica, 2008. Go to original source...




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