Neurol. praxi. 2011;12(4):282-285

Multiple sclerosis and the menopause

doc.MUDr.Peter Koliba, CSc.
Gynekologická ambulance –, Gynartis, s. r. o., Ostrava –, Vřesina

The article is about the relationship between multiple sclerosis (MS) with menopause. MS is an autoimmune, inflammatory, neurodegenerative

disease with chronic course. MS affects patients at a younger age. Improvements in treatment due, that more women are

in menopause and postmenopause age. Women with MS have menopause earlier than is the average age of menopause in a population.

Author discusses the role of changes in levels of sex hormones at menopause and their potential impact on the course of MS.

Keywords: multiple sclerosis (MS), menopause, hormones, ovarian function, premature menopause, hormonal therapy

Published: July 29, 2011  Show citation

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Koliba P. Multiple sclerosis and the menopause. Neurol. praxi. 2011;12(4):282-285.
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References

  1. Correale J, Arias M, Gilmore W. Steroid hormone regulation of cytokine secretion by proteolipid protein-specific CD4 T cell clones isolated from multiple sclerosis patients and normal control subjects. J Immunol 1998; 161: 3365-3374. Go to original source...
  2. Cutolo M, Sulli A, Seriolo B, Accardo S, Masi AT. Estrogens, the immune response and autoimmunity. Clin Exp Rheumatol 1995; 13: 217-226. Go to PubMed...
  3. Donát J. Fyziologické změny v klimakteriu a postmenopauze. Moderní gynekologie a porodnictví 1995; 5: 19.
  4. Grinsted L, Heltberg A, Hagen C, Djursing H. Serum sex hormone and gonadotropine concentrations in premenopausal women with multiple sclerosis J Internal Medicine 1989; 226: 241-244. Go to original source... Go to PubMed...
  5. Havrdová E. Nová diagnostická kritéria RS a jejich praktické důsledky. In: Neurologie 2003 (Eds. Havrdová E, et al.). Praha, Triton 2003: 181-187.
  6. Havrdová E, Horáková D. Roztroušená skleróza. Postgraduální med. 2004; 4: 6.
  7. Havrdová E. Léčba roztroušené sklerózy. Remedia, 2007; 17: 61-72.
  8. Kim S, Liva SM, Dalal MA, Verity MA, Vaskuhl RR. Estriol ameliorates autoimmune demyelinating disease: implications for multiple sclerosis. Neurology 1999; 52: 1230-1238. Go to original source... Go to PubMed...
  9. Kolár OJ. New treatment and azathioprine in multiple sclerosis. Lancet, 1997; 35: 1033. Go to original source... Go to PubMed...
  10. Koliba P, Zapletalová O, Petzel M. Vliv gravidity na průběh roztroušené mozkomíšní sklerózy, Čes. a Slov. Neurol. N, 69/102, 2006; 2: 125-129.
  11. Pozzilli C, Falaschi P, Mainero C, Martocchia A, D'Urso R, Proietti A, Frontoni M, Bastianello S, Filippi M. MRI in multiple sclerosis during the menstrual cycle: relationship with sex hormone patterns. Neurology 1999; 53: 622-624. Go to original source... Go to PubMed...
  12. Smith R, Studd JW. A pilot study of the effect upon multiple sclerosis of the menopause, hormone replacement therapy and the menstrual cycle. J R Soc Med 1992; 85: 612-613. Go to original source... Go to PubMed...
  13. Wei T, Stafford L, Lightman L. The neuroendocrine axis in patiens with multiple sclerosis, Brain, 1997; 120: 1067 - 1076. Go to original source... Go to PubMed...
  14. Zapletalová O. Komplexní léčba roztroušené sklerózy mozkomíšní. Postgraduální med. 2009; 9: 956.




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