Neurol. praxi. 2012;13(2):87-91

The postprocessing of MRI in patients with intractable epilepsy

MUDr.Martin Pail^1,2, Ing.Radek Mareček¹, prof.MUDr.Milan Brázdil, Ph.D.^1,2

¹ Středoevropský technologický institut (CEITEC), Masarykova univerzita, Brno

² Centrum pro epilepsie Brno, 1. neurologická klinika LF MU a FN u sv. Anny, Brno

Epilepsy is one of the most common neurologic disease. Despite the improvement of the neuroimaging methods several structural

pathologies (especially malformations of the cortical development – MCD), which are in the clear-cut causation of disease, do not have

to be detected by classical CT or MRI examination. Because visual evaluation of MRI remains difficult to detect some subtle abnormalities,

several neuroimaging approaches, methods and modalities have been established to improve detection and localization of MCD.

These methods are called in expert literature as a MRI postprocessing. (Jackson at al., 2010). This specific approaches enable to detect

the morphological changes of brain structure not detected by visually inspections of MRI scans and due to their superior contribution

in the determination of MCD, they might be the indivisible part of a presurgical evaluation of brain.

Keywords: voxel–based morphometry, automatic curvilinear model, junctions, intractable epilepsy, focal cortical dysplasia

Published: April 23, 2012  Show citation