Neurol. praxi. 2015;16(4):193-195

Acute mountain sickness

prof. MUDr. Egon Kurča, PhD.1, MUDr. ©tefan Sivák, PhD.1, MUDr. Vladimír Nosáµ, PhD.1, prof. MUDr. Frantiąek Novomeský, PhD.2
1 Neurologická klinika JLF UK a UNM, Martin
2 Ústav súdneho lekárstva a medicínskych expertíz JLF UK a UNM, Martin

Acute mountain sickness (AMS) is a syndrome or a continuum of medical conditions ranging from mild headache to a polysymptomatic life-threatening condition with an underlying combination of cerebral oedema with pulmonary oedema. The common feature of these diagnoses is exceeding the altitude and performance capacity in a particular person during a rapid ascent to high mountain grounds without adequate acclimatization. The review article deals with the clinical presentation of AMS, the pathophysiology, and options of effectively preventing its development or subsequent therapeutic procedures required.

Keywords: high altitude, hypoxia, altitude illness, mountain sickness

Published: September 19, 2015  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Kurča E, Sivák ©, Nosáµ V, Novomeský F. Acute mountain sickness. Neurol. praxi. 2015;16(4):193-195.
Download citation

References

  1. Bärtsch P, Swenson ER. Acute high altitude illnesses. N Engl J Med. 2013?368:2294-2302. Go to original source... Go to PubMed...
  2. Beall CM. Tibetan and Andean patterns of adaptation to high altitude hypoxia. Hum Biol. 2000? 72: 201-228. Go to PubMed...
  3. Burtscher M, Bachmann O, Hatzl T, Hotter B, Likar R, Philadelphy M, Nachbauer W. Cardiopulmonary and metabolic responses in healthy elderly during a one week hiking program at high altitude. Eur J ApplPhysiol. 2001? 84: 379-386. Go to original source... Go to PubMed...
  4. Eide RP, Asplund CA. Altitude illness: update on prevention and treatment. CurrSports Med Rep. 2012? 3: 124-130. Go to original source... Go to PubMed...
  5. Jafarian S, Gorouhi F, Salimi S, Lotfi J. Sumatriptan for prevention of acute mountain sickness: randomized clinical trial. AnnNeurol. 2007? 62: 273-277. Go to original source... Go to PubMed...
  6. Luks AM, McIntosh SE, Grissom CK, Auerbach PS, Rodway GW, Schoene RB, Zafren K, Hackett PH. Wilderness medical society practice guidelines for the prevention and treatment of acute altitude illness: update 2014. Wilderness Environ Med. 2014? (Suppl 4): S4-S14. Go to original source...
  7. Luks AM, Swenson ER. Medication and dosage considerations in the prophylaxis and treatment of high altitude illness. Chest. 2008; 133: 744-755. Go to original source... Go to PubMed...
  8. Maggiorini M, Mélot C, Pierre S, Pfeiffer F, Greve I, Sartori C, Lepori M, Hauser M, Scherrer U, Naeije R. High altitude pulmonary edema is initially caused by an increase in capillary pressure. Circulation. 2001; 103: 2078-2083. Go to original source...
  9. Netzer N, Strohl K, Faulhaber M, Gatterer H, Burtscher M. Hypoxia related altitude illnesses. J Travel Med. 2013?4:247-255. Go to original source...
  10. Richalet JP, Larmignat P, Poitrine E, Letournel M, Canou?-Poitrine F. Physiological risk factorsfor severe high altitude illness: a prospective cohort study. Am J Respir Crit Care Med. 2012? 185: 192-198. Go to original source... Go to PubMed...
  11. Semenza GL. Hypoxiain ducible factors in physiology and medicine. Cell. 2012? 148: 399-408. Go to original source... Go to PubMed...
  12. Simonson TS, Yang Y, Huff CD, Yun H, Qin G, Witherspoon DJ, Bai Z, Lorenzo FR, Xing J, Jorde LB, Prchal JT, Ge R. Genetic evidence for high altitude adaptation in Tibet. Science. 2010? 329: 72-75. Go to original source...
  13. Sutton JR, Coates G, Houston CS. Hypoxia and mountain medicine. Burlington: Queen City Press; 1992: 340.
  14. Swenson ER, Maggiorini M, Mongovin S, Gibbs JS, Greve I, Mairbäurl H, Bärtsch P. Pathogenesis of high altitude pulmonary edema: inflammation is not an etiologic factor. JAMA. 2002? 287: 2228-2235. Go to original source...
  15. West JB. High altitude medicine. Am J Respir Crit Care Med. 2012? 12: 1229-1237. Go to original source...
  16. West JB, Lahiri S, Maret KH, Peters RM Jr, Pizzo CJ. Barometric pressures at extreme altitudes on Mt. Everest: physiological significance. J Appl Physiol. 1983? 54: 1188-1194. Go to original source... Go to PubMed...




Neurology for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.