Neurol. praxi. 2015;16(5):266-268

Neurologic complication of diffuse idiopathic skeletal hyperostosis

prof. MUDr. Ivan Rybár, PhD.

Klinika reumatológie LF SZU a NÚRCH, Piešťany

Diffuse idiopathic skeletal hyperostosis is a non-inflammatory degenerative disease affecting the axial skeleton by calcifications and progressive hyperostosis of anterior and posterior longitudinal ligaments. The disease also affects the peripheral insertions on the shoulders, elbows, pelvic region, knees and heels. In coincidence with rheumatoid arthritis is the disease able to ameliorate its destructive outcomes. In addition to the affected bone and ligaments of spine may be present extraosseal findings such as dysphagia, dysphonia and neurological complications. Of these especially pain in the thoracolumbar spine, stiffness and limitation of mobility, as well as radicular syndrome, myelopathy, thoracic outlet and vertebral fractures. DISH is associated with the metabolic syndrome and its treatment requires in addition to the analgesics, non-steroidal anti-inflammatory drugs, COX-2 inhibitors and myorelaxants, also rehabilitation, physiotherapy and balneotherapy.

Keywords: diffuse idiopathic skeletal hyperostosis, ankylosing vertebral hyperostosis, Forestier disease, neurological complications

Published: October 1, 2015  Show citation