Neurol. praxi. 2016;17(3):117-122 | DOI: 10.36290/neu.2016.038

Rabies and lymphocytic choriomeningitis: clinical manifestation, prophylaxis and therapy

RNDr. Ingeborg Režuchová, PhD.1, Mgr. Lucia Turianová1, RNDr. Katarína Lopušná, PhD.1, doc.RNDr. Peter Kabát, CSc.1,2
1 Virologický ústav, Biomedicínske centrum, Slovenská akadémia vied, Bratislava
2 Katedra mikrobiológie a virológie, Prírodovedecká fakulta UK, Bratislava

The nervous system is the most complicated system of our body and any damage leads to lifelong consequences. As well as the tireless development of science and research, evolve viruses too. Their properties and mechanisms of change adapt to the environment, in which they are located. Therefore, it is necessary to study the molecular properties of the viruses, the way they avoid the immune response, and the therapy and prophylaxis. The aim of this work is to give a comprehensive picture of two neuropathogenic viruses extended almost all over the world, rabies virus and lymphocytic choriomeningitis virus, including their pathogenesis, treatment and prophylaxis.

Keywords: CNS, encephalitis, rabies virus, lymphocytic choriomeningitis virus, antiviral therapy

Published: August 1, 2016  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Režuchová I, Turianová L, Lopušná K, Kabát P. Rabies and lymphocytic choriomeningitis: clinical manifestation, prophylaxis and therapy. Neurol. praxi. 2016;17(3):117-122. doi: 10.36290/neu.2016.038.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Albertini AAV, Ruigrokt RWH, Blondel D. Rabies virus transcription and replication. In Jackson AC, ed. Advances in virus research. 1st ed. Filadelfia: Elsevier; 2011: 1-22. Go to original source...
    2. Armstrong C, Lillie RD. Experimental lymphocytic choriomeningitis of monkeys and mice produced by a virus encountered in studies of the 1933 St. Louis encephalitis epidemic. Public Health Reports. 1934; 49(35): 1019-1022. Go to original source...
    3. Asnis DS, Muana O, Kim DG, Garcia M, Rollin PE, Slavinski S. Lymphocytic choriomeningitis virus meningitis, New York, NY, USA, 2009. Emerg Infect Dis. 2010; 16(2): 328-330. Go to original source... Go to PubMed...
    4. Barton LL, Mets MB. Congenital lymphocytic choriomeningitis virus infection: decade of rediscovery. Clin Infect Dis. 2001; 33(3): 370-374. Go to original source... Go to PubMed...
    5. Bourhy H, Reynes JM, Dunham EJ, Dacheux L, Larrous F, Huong VT, Xu G, Yan J, Miranda ME, Holmes EC. The origin and phylogeography of dog rabies virus. J Gen Virol. 2008; 89(11): 2673-2681. Go to original source... Go to PubMed...
    6. Consales CA, Bolazn VL. Rabies review: immunopathology, clinical aspects and treatment. J Venom Anim Toxins incl Trop Dis. 2007; 13(1): 5-38. Go to original source...
    7. Constantine DG. Bat rabies and other lyssavirus infections. Reston (VA): U.S. Geological Survey Circular; 2009: 68. Go to original source...
    8. De La Torre JC. Molecular and cell biology of the prototypic arenavirus LCMV: implications for understanding and combating hemorrhagic fever arenaviruses. Ann N Y Acad Sci. 2009; 1171: 57-64. Go to original source... Go to PubMed...
    9. Dietzschold B, Li J, Faber M, Schnell M. Concepts in the pathogenesis of rabies. Future Virol. 2008; 3(5): 481-490. Go to original source... Go to PubMed...
    10. Gregg MB. Recent outbreaks of lymphocytic choriomeningitis in the United States. Bull World Health Organ. 1975; 52(4-6): 549-553. Go to PubMed...
    11. Guleria A, Kiranmayi M, Sreejith R, Kumar K, Sharma SK, Gupta S. Reviewing host proteins of rhabdoviridae: Possible leads for lesser studied viruses. J Biosci. 2011; 36(5): 929-937. Go to original source... Go to PubMed...
    12. Hooper DC, Roy A, Kean RB, Phares TW, Barkhouse DA. Therapeutic immune clearance of rabies virus from the CNS. Future Virol. 2011; 6(3): 387-397. Go to original source... Go to PubMed...
    13. Chopy D, Pothlichet J, Lafage M, Mégret F, Fiette L, Si-Tahar M, Lafon M. Ambivalent role of the innate immune response in rabies virus pathogenesis. J Virol. 2011; 85(13): 6657-6668. Go to original source... Go to PubMed...
    14. Jackson AC. Rabies: Scientific basis of the disease and its management. 3rd ed. Londýn: Elsevier; 2013: 704.
    15. Jackson AC. Rabies virus infection: An update. Journal of NeuroVirology. 2003; 9(2): 253-258. Go to original source... Go to PubMed...
    16. Jamieson DJ, Kourtis AP, Bell M, Rasmussen SA. Lymphocytic choriomeningitis virus: an emerging obstetric pathogen? Am J Obstet Gynecol. 2006; 194(6): 1532-1536. Go to original source... Go to PubMed...
    17. Košťálová Z, Kuková Z, Švec P. Lexikón očkovacích látok registrovaných v SR. Via Practica. 2008; 2: 1-48.
    18. Laposova K, Lukacikova L, Oveckova I, Breza J, Pastorekova S, Pastorek J, Tomaskova J. Prevalence of LCMV in patients with renal carcinoma. IUMS 2014. Montreal, Canada: International Union of Microbiological Societies, Congresses. July 27 - August 1, 2014. Montreal, Canada: 2014: 1003.
    19. Lapošová K, Pastoreková S, Tomášková J. Lymphocytic choriomeningitis virus: invisible but not innocent. Acta virologica. 2013; 57(2): 160-170. Go to original source... Go to PubMed...
    20. Moreno H. Ribavirin can be mutagenic for arenaviruses. J Virol. 2011; 85(14): 7246-7255. Go to original source... Go to PubMed...
    21. Plotkin SA, Orenstein WA, Offit PA. Vaccines. 6th ed. Edinburgh: Elsevier; 2012: 1570.
    22. Rabies portal of The World Organisation for Animal Health (OIE) [online]. Dostupné z: <http://www.oie.int/animal-health-in-the-world/rabies-portal/>.
    23. Rajčáni J, Čiampor F. Lekárska virológia. 1 vyd. Bratislava: VEDA; 2006: 680.
    24. Schatz J, Fooks AR, McElhinney L, Horton D, Echevarria J, Vázquez-Moron S, Kooi EA, Rasmussen TB, Müller T, Freuling CM. Bat rabies surveillance in Europe. Zoonoses Public Health. 2013; 60(1): 22-34. Go to original source... Go to PubMed...
    25. Scheld WM, Whitley RJ, Marra CHM. Infections of the central nervous system. 3rd ed. Filadelfia: Lippincott Williams & Wilkins; 2004: 960.
    26. Singh SK, Ružek D. Neuroviral infections: General principles and DNA viruses. 1st ed. USA: CRC Press/Taylor & Francis Group; 2013: 374. Go to original source...
    27. Stein LT, Rech RR, Harrison L, Brown CC. Immunohistochemical study of rabies virus within the central nervous system of domestic and wildlife species. Vet Pathol. 2010; 47(4): 630-633. Go to original source... Go to PubMed...
    28. Suja MS, Mahadevan A, Madhusudana SN, Shankar SK. Role of apoptosis in rabies viral encephalitis: a comparative study in mice, canine, and human brain with a review of literature. Patholog Res Int. 2011; 2011: 374286. Go to original source... Go to PubMed...
    29. Štátna veterinárna a potravinová správa Slovenskej Republiky [online]. Available from: <http://www.svps.sk/zvierata/choroby_besnota.asp>.
    30. Tsiang H. Evidence for an intraaxonal transport of fixed and street rabies virus. J Neuropathol Exp Neurol. 1979; 38(3): 286-299. Go to original source... Go to PubMed...
    31. Yousaf MZ, Qasim M, Zia S, Khan MR, Ashfaq UA, Khan S. Rabies molecular virology, diagnosis, prevention and treatment. Virology Journal. 2012; 9: 50. Go to original source... Go to PubMed...

    Return to the content


    Neurology for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.