Neurol. praxi. 2017;18(2):117-120 | DOI: 10.36290/neu.2017.130
Chronic migraine (CM) is a neurological disease that remains underdiagnosed and difficult to treat. In the comparison with episodic
migraine, patients with CM show a higher degree conditional functional limitation, reduced work productivity and quality
of life. This personal and socioeconomic burden emphasizes the urgent need for adequate treatment. Although we commonly
use a wide range of oral preventatives in the clinical practice, currently the only the Food and Drug Administration (FDA) approved
treatment for CM prevention is onabotulinumtoxin A. In this review, we discuss history and present perspectives of this therapy.
Received: August 7, 2018; Accepted: September 24, 2018; Prepublished online: September 24, 2018; Published: May 1, 2017 Show citation