Neurol. praxi 2018; 19(Suppl.1): 15-18 | DOI: 10.36290/neu.2018.143

Ginkgo biloba EGb761 extract and its use in psychiatry

doc. MUDr. Roman Jirák, CSc.
Psychiatrická klinika 1. Lékařské fakulty UK a Všeobecné fakultní nemocnice, Praha

Ginkgo Biloba extract EGb761 constitutes the mixture of many active substances with different pharmacological activities. Finaleffect is synergistic. Main effects are nootropic, neuroprotective, scavenging of free radicals, hemorrheologic. The outcomes ofmany clinical studies in dementia are ambiguous, but most of them demonstrate mild to medium improvement of cognition andnon-cognitive symptoms of dementia. That is why EGb761 is establisched for the treatment of mild cognitive impairment andmild dementias of Alzheimer´s type, for the treatment of vascular dementias and mixed dementias, also as an add-on therapy toacetylcholinesterase inhibitors and memantine. Effectiveness of EGb761 on the improvement of functional sexual disorders andprobace anxiolytik effect are investigated.

Keywords: Alzheimer´s disease, dementia, extractum Ginkgo biloba, cognitive functions, vascular dementia

Published: August 1, 2018  Show citation

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Jirák R. Ginkgo biloba EGb761 extract and its use in psychiatry. Neurol. praxi. 2018;19(Demence - strašák 21. století):15-18. doi: 10.36290/neu.2018.143.
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