Neurol. praxi. 2022;23(1):33-35 | DOI: 10.36290/neu.2021.069
Neuropsychiatric comorbidities in patients with DMD
- Klinika dětské neurologie LF MU a FN Brno
Duchenne/Becker muscular dystrophy, caused by mutations in dystrophin gene,is one of the most frequent muscular dystrophies. Symptoms of DMD include typical movement problems, cardiomyopathy and respiratory failure most often occur in the third decade. In many patients we can find not only movement problems but also neuropsychiatric disorders, esp. autism spectrum disorders, attention-deficit hyperactivity disorder and obsessive-compulsive disorder. Their incidence is higher than in other population. Probabaly it due to lack of dystrophin in neurons.
Keywords: Duchenne/Becker muscular dystrophy, autism spectrum disorders, attention-deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD).
Received: August 12, 2021; Revised: September 14, 2021; Accepted: September 15, 2021; Prepublished online: September 15, 2021; Published: March 14, 2022 Show citation
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