Neurol. praxi. 2023;24(5):374-378 | DOI: 10.36290/neu.2023.023

Fitness to drive in Parkinson's disease: current issues

MUDr. Petr Hollý1, 2
1 Neurologická klinika a Centrum klinických neurověd 1. lékařské fakulty Univerzity Karlovy a Všeobecné fakultní nemocnice v Praze
2 Ústav soudního lékařství a toxikologie 1. lékařské fakulty Univerzity Karlovy a Všeobecné fakultní nemocnice v Praze

Parkinson's disease (PD) is a very common progressive disease and driving is a demanding and complex activity that requires the interplay of cognitive and psychomotor functions, good planning, memory, attention and eye-hand-foot coordination. The decision to be unable to drive is of paramount importance to the patient, but we must also keep road safety in mind. Patients with PD have a higher incidence of cognitive impairment and impaired mobility is also involved in driving problems. In addition, the incidence of excessive daytime sleepiness, which can be potentiated by medication, is a problem. Daytime sleepiness should be specifically asked about. At present, there are no uniform legal criteria to follow.

Keywords: Parkinson's disease, excessive daytime sleepiness, driving.

Received: March 3, 2023; Revised: April 13, 2023; Accepted: April 27, 2023; Prepublished online: April 27, 2023; Published: October 30, 2023  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Hollý P. Fitness to drive in Parkinson's disease: current issues. Neurol. praxi. 2023;24(5):374-378. doi: 10.36290/neu.2023.023.

Download citation

References

  1. Aarsland D, Andersen K, Larsen JP, et al. Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study. Arch Neurol. 2003;60(3):387-392. doi:10.1001/archneur.60. 3. 387. Go to original source...
  2. Adler CH, Caviness JN, Hentz JG, et al. Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease. Mov Disord. 2003;18(3):287-293. doi:10.1002/mds.10390. Go to original source... Go to PubMed...
  3. Bareš M. Zvýšená denní spavost a ataky náhlého usnutí u pacientů s Parkinsonovou nemocí: nadešel čas na všeobecný konsenzus ohledně způsobilosti řízení motorových vozidel? Neurol. praxi. 2004;1:36-38.
  4. Borek LL, Kohn R, Friedman JH. Mood and sleep in Parkinson's disease. J Clin Psychiatry. 2006;67(6):958-963. doi:10.4088/jcp.v67n0613. Go to original source... Go to PubMed...
  5. Brodsky MA, Godbold J, Roth T, et al. Sleepiness in Parkinson's disease: a controlled study. Mov Disord. 2003;18(6):668-672. doi:10.1002/mds.10429. Go to original source... Go to PubMed...
  6. Buhmann C, Maintz L, Hierling J, et al. Effect of subthalamic nucleus deep brain stimulation on driving in Parkinson disease. Neurology. 2014;82(1):32-40. doi:10.1212/01.wnl.0000438223.17976.fb. Go to original source... Go to PubMed...
  7. Crizzle AM, Myers AM, Roy EA, et al. Drivers with Parkinson's disease: are the symptoms of PD associated with restricted driving practices? J Neurol. 2013;260(10):2562-2568. doi:10.1007/s00415-013-7017-9. Go to original source... Go to PubMed...
  8. da Silva­‑Junior FP, do Prado GF, Barbosa ER, et al. Sleep disordered breathing in Parkinson's disease: a critical appraisal. Sleep Med Rev. 2014;18(2):173-178. doi:10.1016/j.smrv.2013. 04. 005. Go to original source...
  9. Devos H, Vandenberghe W, Tant M, et al. Driving and off­‑road impairments underlying failure on road testing in Parkinson's disease. Mov Disord. 2013;28(14):1949-1956. doi:10.1002/mds.25701. Go to original source... Go to PubMed...
  10. Dubinsky RM, Gray C, Husted D, et al. Driving in Parkinson's disease. Neurology. 1991;41(4):517-520. doi:10.1212/wnl.41. 4. 517. Go to original source...
  11. Dubois B, Pillon B. Cognitive deficits in Parkinson's disease. J Neurol. 1997;244(1):2-8. doi:10.1007/pl00007725. Go to original source... Go to PubMed...
  12. Emerson JL, Johnson AM, Dawson JD, et al. Predictors of driving outcomes in advancing age. Psychol Aging. 2012;27(3):550-559. doi:10.1037/a0026359. Go to original source... Go to PubMed...
  13. Frucht S, Rogers JD, Greene PE, et al. Falling asleep at the wheel: motor vehicle mishaps in persons taking pramipexole and ropinirole. Neurology. 1999;52(9):1908-1910. doi:10.1212/wnl.52. 9. 1908. Go to original source...
  14. Hirsch L, Jette N, Frolkis A, et al. The Incidence of Parkinson's Disease: A Systematic Review and Meta­‑Analysis. Neuroepidemiology. 2016;46(4):292-300. doi:10.1159/000445751. Go to original source... Go to PubMed...
  15. Hogl B, Saletu M, Brandauer E, et al. Modafinil for the treatment of daytime sleepiness in Parkinson's disease: a double­‑blind, randomized, crossover, placebo­‑controlled polygraphic trial. Sleep. 2002;25(8):905-909. doi: Go to original source...
  16. Homann CN, Suppan K, Homann B, et al. Driving in Parkinson's disease - a health hazard? J Neurol. 2003;250(12): 1439-1446. doi:10.1007/s00415-003-0239-5. Go to original source... Go to PubMed...
  17. Chahine LM, Amara AW, Videnovic A. A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease from 2005 to 2015. Sleep Med Rev. 2017;35:33-50. doi:10.1016/j.smrv.2016. 08. 001. Go to original source...
  18. Chaudhuri KR, Naidu Y. Early Parkinson's disease and non­‑motor issues. J Neurol. 2008;255 Suppl 5:33-38. doi:10.1007/s00415-008-5006-1. Go to original source... Go to PubMed...
  19. Lings S, Dupont E. Driving with Parkinson's disease. A controlled laboratory investigation. Acta Neurol Scand. 1992;86(1):33-39. doi:10.1111/j.1600-0404.1992.tb08050.x. Go to original source... Go to PubMed...
  20. Littner MR, Kushida C, Wise M, et al. Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test. Sleep. 2005;28(1):113-121. doi:10.1093/sleep/28. 1. 113. Go to original source...
  21. Madeley P, Hulley JL, Wildgust H, et al. Parkinson's disease and driving ability. J Neurol Neurosurg Psychiatry. 1990;53(7):580-582. doi:10.1136/jnnp.53. 7. 580. Go to original source...
  22. Meindorfner C, Korner Y, Moller JC, et al. Driving in Parkinson's disease: mobility, accidents, and sudden onset of sleep at the wheel. Mov Disord. 2005;20(7):832-842. doi:10.1002/mds.20412. Go to original source... Go to PubMed...
  23. Michon JLE, Schwing RC (Eds.). Human behavior and traffic safety. New York: Plenum Press. 1985; 485-520 s. ISBN 0306422255.
  24. Naismith SL, Terpening Z, Shine JM, et al. Neuropsychological functioning in Parkinson's disease: differential relationships with self­‑reported sleep­‑wake disturbances. Mov Disord. 2011;26(8):1537-1541. doi:10.1002/mds.23640. Go to original source... Go to PubMed...
  25. Ondo WG, Fayle R, Atassi F, et al. Modafinil for daytime somnolence in Parkinson's disease: double blind, placebo controlled parallel trial. J Neurol Neurosurg Psychiatry. 2005;76(12):1636-1639. doi:10.1136/jnnp.2005.065870. Go to original source... Go to PubMed...
  26. Ondo WG, Perkins T, Swick T, et al. Sodium oxybate for excessive daytime sleepiness in Parkinson disease: an open­‑label polysomnographic study. Arch Neurol. 2008;65(10):1337-1340. doi:10.1001/archneur.65. 10. 1337. Go to original source...
  27. Poryazova R, Oberholzer M, Baumann CR, et al. REM sleep behavior disorder in Parkinson's disease: a questionnaire­‑based survey. J Clin Sleep Med. 2013;9(1):55-59 A. doi:10.5664/jcsm.2340. Go to original source... Go to PubMed...
  28. Prohlášení posuzované osoby ke své zdravotní způsobilosti. [Cit. 1. 3. 2021]. Dostupné na: https://www.zakonyprolidi.cz/disk/cs/file/2004/2004c089z0277_2015c110z0271p001u001.pdf.
  29. Ranchet M, Devos H, Uc EY. Driving in Parkinson Disease. Clin Geriatr Med. 2020;36(1):141-148. doi:10.1016/j.cger.2019. 09. 007. Go to original source...
  30. Ranchet M, Paire­‑Ficout L, Uc EY, et al. Impact of specific executive functions on driving performance in people with Parkinson's disease. Mov Disord. 2013;28(14):1941-1948. doi:10.1002/mds.25660. Go to original source... Go to PubMed...
  31. Rolinski M, Szewczyk­‑Krolikowski K, Tomlinson PR, et al. REM sleep behaviour disorder is associated with worse quality of life and other non­‑motor features in early Parkinson's disease. J Neurol Neurosurg Psychiatry. 2014;85(5):560-566. doi:10.1136/jnnp-2013-306104. Go to original source... Go to PubMed...
  32. Svátová J. Vliv Parkinsonovy nemoci na schopnost řídit motorová vozidla. Interní Med. 2010;12(4):205-208. doi:
  33. Tholfsen LK, Larsen JP, Schulz J, et al. Development of excessive daytime sleepiness in early Parkinson disease. Neurology. 201585(2):162-168. doi:10.1212/WNL.0000000000001737. Go to original source... Go to PubMed...
  34. Uc EY, Rizzo M, Anderson SW, et al. Visual dysfunction in Parkinson disease without dementia. Neurology. 2005;65(12):1907-1913. doi:10.1212/01.wnl.0000 191565.11065. 11. Go to original source...
  35. Uc EY, Rizzo M, Anderson SW, et al. Driving with distraction in Parkinson disease. Neurology. 2006;67(10):1774-1780. doi:10.1212/01.wnl.0000245086.32787. 61. Go to original source...
  36. Uc EY, Rizzo M, Anderson SW, et al. Impaired navigation in drivers with Parkinson's disease. Brain. 2007;130(Pt 9):2433-2440. doi:10.1093/brain/awm178. Go to original source... Go to PubMed...
  37. Verbaan D, van Rooden SM, Visser M, et al. Nighttime sleep problems and daytime sleepiness in Parkinson's disease. Mov Disord. 2008;23(1):35-41. doi:10.1002/mds.21727. Go to original source... Go to PubMed...
  38. Zesiewicz TA, Cimino CR, Malek AR, et al. Driving safety in Parkinson's disease. Neurology. 2002;59(11):1787-1788. doi:10.1212/01.wnl.0000035636.83680.c6. Go to original source... Go to PubMed...




Neurology for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.