Neurol. praxi. 2024;25(5):342-346 | DOI: 10.36290/neu.2024.030

Hypertension and neurological diseases

MUDr. Petr Mikulenka, prof. MUDr. Ivana Štětkářová, CSc., MBA
Neurologická klinika, 3. LF UK a FNKV, Praha

Hypertension, defined as an increase in blood pressure above 140/90 mmHg, is associa­ted with damage to a number of organs, including the brain. Clinical manifestations include hypertensive encephalopathy, posterior reversible encephalopathy syndrome, and cerebrovascular accidents. Chronic hypertension contributes to structural and functional changes in brain tissue, which can lead to clinically manifest impairment of cognitive functions and the development of dementia. The pathophysiological basis of brain damage induced by hypertension is complex. Early detection of hypertension and its adequate treatment are crucial for reducing the risk of neurological complications.

Keywords: brain, hypertension, stroke, hypertensive encephalopathy, PRES, eclampsia, dementia, autoregulation, antihypertensives.

Received: February 15, 2024; Revised: April 29, 2024; Accepted: May 6, 2024; Prepublished online: May 6, 2024; Published: November 19, 2024  Show citation

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Mikulenka P, Štětkářová I. Hypertension and neurological diseases. Neurol. praxi. 2024;25(5):342-346. doi: 10.36290/neu.2024.030.
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