Neurol. praxi. 2025;26(3):225-229 | DOI: 10.36290/neu.2024.050

Sleep disorders in neurological diseases

doc. MUDr. Jitka Bušková, Ph.D.
Oddělení spánkové medicíny, NÚDZ Klecany

Sleep plays a significant role in neurology. There is a very close relationship between sleep quality or duration and individual neurological diseases. Poor quality sleep adversely affects the course of a number of neurological diseases, such as cerebrovascular, autoimmune, and neuromuscular ones, and may increase the rates of epileptic or migrainous attacks. Sleep apnoea is also an independent risk factor for the development of stroke. Sleep disorders may precede Alzheimer's disease or represent a prodromal stage of other neurodegenerative diseases. Interventions to improve the quality of sleep and treatment of specific sleep disorders can play an important role in preventing neurological diseases as well as often improve their course.

Keywords: sleep disorders, neurological diseases, sleep apnoea, insomnia, hypersomnia, parasomnia, circadian rhythm disorders.

Received: August 15, 2024; Revised: August 15, 2024; Accepted: August 16, 2024; Prepublished online: August 16, 2024; Published: July 4, 2025  Show citation

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Bušková J. Sleep disorders in neurological diseases. Neurol. praxi. 2025;26(3):225-229. doi: 10.36290/neu.2024.050.
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References

  1. . Aoun R, Rawal H, Attarian H, et al. Impact of traumatic brain injury on sleep: an overview. Nat Sci Sleep. 2019;11:131-140. doi:10.2147/NSS.S182158. Go to original source... Go to PubMed...
  2. . Carter J. Fatigue in patients with multiple sclerosis. 2018.
  3. . Figueiro MG. Light, sleep and circadian rhythms in older adults with Alzheimer's disease and related dementias. Neurodegener Dis Manag. 2017;7(2):119-145. doi:10.2217/nmt-2016-0060. Go to original source... Go to PubMed...
  4. . Foschi M, Rizzo G, Liguori R, et al. Sleep-related disorders and their relationship with MRI findings in multiple sclerosis. Sleep Med. 2019;56:90-97. doi:10.1016/j.sleep.2019.01.010. Go to original source... Go to PubMed...
  5. . Chio A, Calvo A, Moglia C, et al. Non-invasive ventilation in amyotrophic lateral sclerosis: a 10 year population based study. J Neurol Neurosurg Psychiatry. 2012;83(4):377-81. doi:10.1136/jnnp-2011-300472. Go to original source... Go to PubMed...
  6. . Johnson KGandJohnson DC. Frequency of sleep apnea in stroke and TIA patients: a meta-analysis. J Clin Sleep Med. 2010;6(2):131-7. Go to original source...
  7. . Kaminska M, Mery VP, Lafontaine AL, et al. Change in Cognition and Other Non-Motor Symptoms With Obstructive Sleep Apnea Treatment in Parkinson Disease. J Clin Sleep Med. 2018;14(5):819-828. doi:10.5664/jcsm.7114. Go to original source... Go to PubMed...
  8. . Kanbayashi T, Shimohata T, Nakashima I, et al. Symptomatic narcolepsy in patients with neuromyelitis optica and multiple sclerosis: new neurochemical and immunological implications. Arch Neurol. 2009;66(12):1563-6. doi:10.1001/archneurol.2009.264. Go to original source... Go to PubMed...
  9. . Koltuniuk A, Kazimierska-Zajac M, Poglodek D, et al. Sleep Disturbances, Degree of Disability and the Quality of Life in Multiple Sclerosis Patients. Int J Environ Res Public Health. 2022;19(6)doi:10.3390/ijerph19063271. Go to original source... Go to PubMed...
  10. . Koo DL, Nam H, Thomas R, et al. Sleep disturbances as a risk factor for stroke. J Stroke. 2018;20(1):12-32. Go to original source... Go to PubMed...
  11. . Korostovtseva LSandKolomeichuk SN. Circadian Factors in Stroke: A Clinician's Perspective. Cardiol Ther. 2023;12(2):275-295. doi:10.1007/s40119-023-00313-w. Go to original source... Go to PubMed...
  12. . Liu Y, Partinen E, Chan NY, et al. Dream-enactment behaviours during the COVID-19 pandemic: an international COVID-19 sleep study. J Sleep Res. 2023;32(1):e13613. doi:10.1111/jsr.13613. Go to original source... Go to PubMed...
  13. . Miller RG, Jackson CE, Kasarskis EJ, et al. Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: multidisciplinary care, symptom management, and cognitive/behavioral impairment (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2009;73(15):1227-33. doi:10.1212/WNL.0b013e3181bc01a4. Go to original source... Go to PubMed...
  14. . Moore JL, Carvalho DZ, St Louis EK, et al. Sleep and Epilepsy: a Focused Review of Pathophysiology, Clinical Syndromes, Co-morbidities, and Therapy. Neurotherapeutics. 2021;18(1):170-180. doi:10.1007/s13311-021-01021-w. Go to original source... Go to PubMed...
  15. . Nobili L, Beniczky S, Eriksson SH, et al. Expert Opinion: Managing sleep disturbances in people with epilepsy. Epilepsy Behav. 2021;124:108341. doi:10.1016/j.yebeh.2021.108341 Go to original source... Go to PubMed...
  16. . Nobili L, Proserpio P, Rubboli G, et al. Sudden unexpected death in epilepsy (SUDEP) and sleep. Sleep Med Rev. 2011;15(4):237-46. doi:10.1016/j.smrv.2010.07.006. Go to original source... Go to PubMed...
  17. . Parra O, Arboix A, Bechich S, et al. Time course of sleep-related breathing disorders in first-ever stroke or transient ischemic attack. Am J Respir Crit Care Med. 2000;161(2 Pt 1):375-80. doi:10.1164/ajrccm.161.2.9903139. Go to original source... Go to PubMed...
  18. . Pornsriniyom D, Kim H, Bena J, et al. Effect of positive airway pressure therapy on seizure control in patients with epilepsy and obstructive sleep apnea. Epilepsy Behav. 2014;37:270-5. doi:10.1016/j.yebeh.2014.07.005. Go to original source... Go to PubMed...
  19. . Postuma RB, Iranzo A, Hu M, et al. Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study. Brain. 2019;142(3):744-759. doi:10.1093/brain/awz030. Go to original source... Go to PubMed...
  20. . Sabia S, Fayosse A, Dumurgier J, et al. Association of sleep duration in middle and old age with incidence of dementia. Nat Commun. 2021;12(1):2289. doi:10.1038/s41467-021-22354-2. Go to original source... Go to PubMed...
  21. . Sahlin C, Sandberg O, Gustafson Y, et al. Obstructive sleep apnea is a risk factor for death in patients with stroke: a 10-year follow-up. Arch Intern Med. 2008;168(3):297-301. doi:10.1001/archinternmed.2007.70. Go to original source... Go to PubMed...
  22. . Seppi K, Ray Chaudhuri K, Coelho M, et al. Update on treatments for nonmotor symptoms of Parkinson's disease-an evidence-based medicine review. Mov Disord. 2019;34(2):180-198. doi:10.1002/mds.27602. Go to original source... Go to PubMed...
  23. . Shieu MM, Zaheed AB, Shannon C, et al. Positive Airway Pressure and Cognitive Disorders in Adults With Obstructive Sleep Apnea: A Systematic Review of the Literature. Neurology. 2022;99(4):e334-e346. doi:10.1212/WNL.0000000000200383. Go to original source... Go to PubMed...
  24. . Silber MH, Buchfuhrer MJ, Earley CJ, et al. The Management of Restless Legs Syndrome: An Updated Algorithm. Mayo Clin Proc. 2021;96(7):1921-1937. doi:10.1016/j.mayocp.2020.12.026. Go to original source... Go to PubMed...
  25. . Silva-Neto RP, Santos PandPeres MFP. Hypnic headache: A review of 348 cases published from 1988 to 2018. J Neurol Sci. 2019;401:103-109. doi:10.1016/j.jns.2019.04.028. Go to original source... Go to PubMed...
  26. . Tholfsen LK, Larsen JP, Schulz J, et al. Changes in insomnia subtypes in early Parkinson disease. Neurology. 2017;88(4):352-358. doi:10.1212/WNL.0000000000003540. Go to original source... Go to PubMed...
  27. . Thomas A, Greenwald BD. Nonpharmacological management of sleep disturbances after traumatic brain injury. NeuroRehabilitation. 2018;43(3):355-360. doi:10.3233/NRE-182535. Go to original source... Go to PubMed...
  28. . Virani SS, Alonso A, Benjamin EJ, et al. Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association. Circulation. 2020;141(9):e139-e596. doi:10.1161/CIR.0000000000000757. Go to original source... Go to PubMed...
  29. . Wang CandHoltzman D. Bidirectional relationship between sleep and Alzheimer's disease: role of amyloid, tau, and other factors. Neuropsychopharmacology. 2020;45(1):104-120. Go to original source... Go to PubMed...
  30. . Ye D, Chen C, Song D, et al. Oropharyngeal Muscle Exercise Therapy Improves Signs and Symptoms of Post-stroke Moderate Obstructive Sleep Apnea Syndrome. Front Neurol. 2018;9:912. doi:10.3389/fneur.2018.00912. Go to original source... Go to PubMed...
  31. . Zanzmera P, Shukla G, Gupta A, et al. Effect of successful epilepsy surgery on subjective and objective sleep parameters--a prospective study. Sleep Med. 2013;14(4):333-8. doi:10.1016/j.sleep.2012.11.017. Go to original source... Go to PubMed...
  32. . Zhang J, Xu CYandLiu J. Meta-analysis on the prevalence of REM sleep behavior disorder symptoms in Parkinson's disease. BMC Neurol. 2017;17(1):23. doi:10.1186/s12883-017-0795-4. Go to original source... Go to PubMed...




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