Neurol. praxi. 2026;27(3):200-202 | DOI: 10.36290/neu.2025.067
Gold Coast Criteria - new criteria for determination the diagnosis of amyotrophic lateral sclerosis
- 1 Neurologická klinika FZS Univerzity Pardubice a NPK, Pardubice
- 2 Neurologická klinika FNKV a 3. lékařské fakulty UK, Praha
Amyotrophic lateral sclerosis (ALS) is a systemic and fatal neurodegenerative disorder with degeneration of central and peripheral motoneurons, non-motor symptoms and non-interrupted progression of disease. The old diagnostic criteria are very complicated and setting of diagnosis comes late, frequently at the terminal stage of disease. The new diagnostic criteria - Gold Coast criteria - were developed by a group of specialists in 2020 and their implementation in clinical practise will shorten the time to the diagnose setting. This will be advantageous for new treatment introduction, for shortening of repeated and often demanding methods and for providing a precise information for the patient.
Keywords: amyotrophic lateral sclerosis, central and peripheral motoneuron, neurophysiological parameters, genetic investigation.
Received: August 7, 2025; Revised: August 7, 2025; Accepted: August 27, 2025; Prepublished online: August 27, 2025; Published: July 20, 2026 Show citation
References
- Ambler Z. Poruchy periferních nervů. Triton, Praha 2013.
- Andrew AS, Bradley WG, Peipert D, et al. Risk Factors for amyotrophic lateral sclerosis: a regional United States case-control study. Muscle & Nerve. 2021;63:52-59. doi:10.1002/mus.27085.
Go to original source... - Carvalho M, Swash M. Diagnosis and differntial diagnosis of MND/ALS: iFCN handbook chapter. Clinical Neurophysiology Practice. 2024;9:27-38. Go to original source...
- Day B, Kumar A, Patel AB. Pathomechanistic network of motor system injury in amyotrophic lateral sclerosis. Curren Neuropharmacology. 2024;22:1778-1806. doi:10.2174/1570159X21666230824091601. Go to original source...
Go to PubMed... - Feldman EL, Goutman SA, Petri S, et al. Amyotrophic lateral sclerosis. Lancet. 2022;400(10360):1363-1380. doi:10.1016/S0140-6736(22)01272-7. Go to original source... Go to PubMed...
- Turner MR. Criteria ALS: the Gold Coast criteria and the role of EMG. Pract Neurol. 2022;22:176-178. doi:10.1136/practneurol-2021-003256. Go to original source... Go to PubMed...
- Vidovic M, Müschen LH, Brakemeier S, et al. Current state and future directions in the diagnosis of amyotrophic lateral sclerosis. Cells. 2023;12:736. https://doi.org/10.3390/cells12050736. Go to original source...
- Vucic S, Ferguson TA, Cummings C, et al. Gold Coast diagnostic critera: Implications for ALS diagnosis and clinical trial enrollment. Muscle Nerve. 2021;64:532-537. doi:10.1002/mus27392. Go to original source...