Neurol. praxi. 2026;27(3):227-230 | DOI: 10.36290/neu.2025.031

Subacute progressive polyneuropathy as a manifestation of Churg-Strauss syndrome - a case report

MUDr. Kristián ©veda, doc. MUDr. Milan Grofik, PhD., MUDr. Monika Turčánová Kopruąáková, PhD., MUDr. Jana Olekąáková, PhD., prof. MUDr. Egon Kurča, PhD., FESO
Neurologická klinika, Jesseniova lekárska fakulta UK v Martine, Univerzitná nemocnica Martin

Eosinophilic Granulomatosis with Polyangiitis (EGPA), also known as Churg-Strauss Syndrome, is a disease characterized by necrotizing vasculitis affecting medium- and small-caliber arteries. Approximately 40-50 % of patients with EGPA have positive ANCA antibodies and exhibit a "vasculitic" phenotype, presenting with myalgias, migratory polyarthralgias, weight loss, mononeuropathy multiplex, and renal involvement. This article describes the case of a 55-year-old patient with subacute-onset symmetrical axonal polyneuropathy and negative ANCA antibodies, who was diagnosed with EGPA. The presented case highlights the importance of through differential diagnosis in subacute progressive polyneuropathies, emphasizing the need to consider this relatively rare but potentially well-treatable nosological entity.

Keywords: Churg-Strauss syndrome, subacute progressive polyneuropathy, vasculitis.

Received: March 29, 2025; Revised: March 29, 2025; Accepted: March 31, 2025; Prepublished online: March 31, 2025; Published: July 20, 2026  Show citation

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©veda K, Grofik M, Turčánová Kopruąáková M, Olekąáková J, Kurča E. Subacute progressive polyneuropathy as a manifestation of Churg-Strauss syndrome - a case report. Neurol. praxi. 2026;27(3):227-230. doi: 10.36290/neu.2025.031.
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