Neurol. praxi. 2022;23(1):54-56 | DOI: 10.36290/neu.2021.050
The role of biopsy in the diagnosis of neuromuscular disorders in the molecular biological era
- Ústav patologie a molekulární medicíny 2. LF UK a FN v Motole, Praha
Nowadays, in times of new possibilities of molecular genetic testing, muscle biopsy is no longer the diagnostic method of choice in most myopathies. In hereditary myopathies, a biopsy is indicated only if the findings from molecular biological analysis is non-conclusive or does not correlate with the clinical phenotype of the disease. On the contrary, muscle biopsy is indicated in all cases of autoimmune processes - myositis, immune-mediated necrotizing myopathies, or vasculitis.
Keywords: muscle biopsy, myopathy, nerve biopsy, neuropathy.
Received: July 23, 2021; Revised: July 23, 2021; Accepted: July 28, 2021; Prepublished online: July 28, 2021; Published: March 14, 2022 Show citation
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