Neurol. pro Praxi, 2006; 5: 276-281

Účinnost a snášenlivost galantaminu v léčbě Alzheimerovy nemoci

doc. MUDr. Vladimír Pidrman Ph.D1, MUDr. Klára Látalová1, Ing. Karel Chroust Ph.D2
1 Psychiatrická klinika FN a LF UP, Olomouc
2 Přírodovědecká fakulta Masarykovy univerzity v Brně

Autoři prezentují roční otevřené sledování účinnosti a snášenlivosti galantaminu v léčbě Alzheimerovy nemoci u ambulantních pacientů. Hodnoceny byly kognitivní funkce, aktivity denního života a výskyt vedlejších účinků. Do sledování bylo zařazeno 27 pacientů (20 žen, 7 mužů), 13 pacientů bylo ve věku 74 let a méně, 14 nemocných bylo ve věku vyšším než 74 let. Roční sledování dokončilo 20 nemocných půlroční sledování všech 27 nemocných. Důvodem vyřazení byla ve všech případech progrese onemocnění spojená s následnou s dlouhodobou hospitalizací, nikoliv vedlejší účinky. Autoři dále rozlišují a popisují skupinu respondentů a non-respondentů, vyjadřují se k možnosti predikace účinnosti léčby. Sledování prokázalo dobrou účinnost a snášenlivost v léčbě galantaminem.

Keywords: Alzheimerova demence, inhibitory cholinesteráz, galantamin

Published: January 1, 2007  Show citation

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Pidrman V, Látalová K, Chroust K. Účinnost a snášenlivost galantaminu v léčbě Alzheimerovy nemoci. Neurol. praxi. 2006;7(5):276-281.
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