Neurol. praxi. 2008;9(1):54

Má význam prevencia vazospasmov pri traumatickom subarachnoidálnom krvácaní?

prof. MUDr. Juraj Šteňo, CSc.
Neurochirurgická klinika LFUK, FNsP akad. L. Dérera, Bratislava

Indikácia podávania nimodipinu pri traumatickom subarachnoidálnom krvácaní (tSAH) sa opiera o výsledky štúdii z deväťdesiatych rokov, podľa ktorých: a) klinická významnosť tSAH je podobná SAH z prasknutej mozgovej aneuryzmy, b) nepriaznivé výsledky liečenia pacientov s tSAh boli po podávaní nimodipinu signifikantne menej časté v porovnaní s placebom (1, 2). Sami sme pozorovali klinicky významné spazmy­ mozgových tepien po tSAH, čo nás tiež viedlo ku rutínnemu podávaniu nimodipinu. Jeho priaznivý účinok sa však v novšich štúdiach nepotvrdil (3).

Published: March 15, 2008  Show citation

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Šteňo J. Má význam prevencia vazospasmov pri traumatickom subarachnoidálnom krvácaní? Neurol. praxi. 2008;9(1):54.
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    References

    1. Kakarieka A: Review on traumatic subarachnoid hemorrhage. Neurol Res 1997; 19: 230-232. Go to original source... Go to PubMed...
    2. Kakarieka A, Braakman R, Schakel EH: Clinical significance of the finding of subarachnoid blood on CT scan after head injury. Acta Neurochir (Wien) 1994; 129: 1-5. Go to original source... Go to PubMed...
    3. Vergouwen MD, Vermeulen M, Roos YB: Effect of nimodipine on outcome in patients with traumatic subarachnoid haemorrhage: a systematic review. Lancet Neurol. 2006; 5: 1029-1032. Go to original source... Go to PubMed...

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