Neurol. praxi. 2009;10(6):384-389

Treating Alzheimer’s disease and related neurodegenerative dementias

doc.MUDr.Roman Jirák, CSc.

Psychiatrická klinika 1. LF UK Praha

Dementias of neurodegenerative origin represents big therapeutical problem for its frequency (Alzheimer´s disease is most common

dementia), health and social unadvisability (diseases devastating the quality of life and in most cases with letal end), for its financial

expensiveness and for its difficult currability. In most cases of these diseases is not known its ethiology and pathogenesis completely

at present time, and thus our contemporary treatment results from the affection of known pathogenetic mechanisms. Therapy of neurodegenerative

dementias includes pharmacotherapy of cognitive functions, pharmacotherapy of non-cognitive functions, therapy

of intercurrent static disorders, psychotherapy (first of all reeducation), sociotherapy and cooperation with caregivers – closest family

members. In the article there are discussed basic possibilities of above mentioned therapeutic approaches.

Keywords: Alzheimer´s disease, dementia, pharmacotherapy, Lewy body disease, neurodegeneration, reeducation

Published: January 1, 2010  Show citation