Neurol. praxi. 2010;11(4):224-227

Toxic neuropathy

doc.MUDr.Edvard Ehler, CSc., MUDr.Jan Latta

Neurologická klinika, Pardubická krajská nemocnice, a. s.

Fakulta zdravotnických studií, Univerzita Pardubice

We have detected the 2 major trends in toxic neuropathies in our sample-set: i) professional toxic neuropathies incidence has decreased

and ii) the number of drug-induced neuropathies has increased. It was proven that the axonal toxic neuropathies are the most frequent

and long nerves are affected most severely. In clinical findings the lesion of sensory fibers prevails above the motor fibers lesion and

above the signs of autonomic nerve dysfunction. The most important steps in the diagnostic process are the goal adhered history, the

clinical picture, the neurophysiological investigation and blood and urine analysis. If the exposition to the industrial toxin occurred and

is confirmed with the diagnostic process, the cooperation with Centre for occupational medicine is unavoidable. Symptomatic therapy

is always prescribed, with the possible addition of targeted therapy in some toxic neuropathies, to terminate the neurotoxic medication

or stopping the toxic exposition. The basic approach in toxic neuropathies is always the prevention.

Keywords: neurotoxicity, industrial toxins, heavy metals, medicaments, toxic neuropathies

Published: October 1, 2010  Show citation