Neurol. praxi. 2011;12(5):348-351

Current status and perspectives of treatment for brain metastases

MUDr.Markéta Pospíšková, MUDr.Milan Kohoutek, MUDr.Michaela Zábojníková
Oddělení radiační onkologie, KOC KNTB a. s., Zlín

Brain metastases are the most common intracranial neoplasms. The incidence of brain metastases is rising due to earlier detection,

more effective imaging modalities and more effective treatment of systemic disease. The median survival of these patients is without

treatment one month, corticosteroids can extend median survival to 2 months and radiotherapy to 3–6 months. The gold standard was

WBI, but in the last 20 years are most often used stereotactic radiosurgery and stereotactic radiotherapy and neurosurgery for solitar

lesions with improving median survival to 16 months. The goal of my work is to review important treatment modalities in patients with

brain metastases with multidisciplinary approach.

Keywords: brain metastases, whole brain irradiation, stereotactic radiosurgery, stereotactic radiotherapy

Published: November 1, 2011  Show citation

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Pospíšková M, Kohoutek M, Zábojníková M. Current status and perspectives of treatment for brain metastases. Neurol. praxi. 2011;12(5):348-351.
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References

  1. Antonadou D. Current treatment of brain Metastases, Business briefing: European Oncology Review 2005. Go to original source...
  2. Eichler FA, Loeffler SJ. Multidisciplinary Managment of Brain metastases, The Oncologist 2007; 12(7): 884-898. Go to original source... Go to PubMed...
  3. Fadrus P, Lakomý R, Hübnerova P, Slabý O, Keřkovský M, Svoboda T, Vybíhal V, Neuman E, Kryštofová S, Sova M, Smrčka M. Intrakraniální nádory - diagnostika a terapie, Interní Med. pro praxi 2010; 12(7 a 8): 376-378.
  4. Jančálek R, Chrastina J, Novák Z, Feitová V, Slabá B, Hermanová M, Říha J. Význam stereotaktické biopsie mozkových expanzivních procesů v diagnostice metastatického nádorového onemocnění, 2004 XXVIII. BOD, databáze abstrakt.
  5. Klener P, Abrahámová J, Fait V, Mališ J, Matějovský Z, Petruželka L, Žaloudík J. Klinická onkologie, Galén, Karolinum 2002; 357: 307-308.
  6. Kunthia D, Brown P, Li J, Mehta MP. Whole-brain radiotherapy in the management of brain metastasis. J Clin Oncol. 2006; 24: 1295-1304. Go to original source... Go to PubMed...
  7. Langer CJ, Mehta MP. Current management of brain metastases, with a focus on systemic options. J Clin Oncol. 2005; 23: 6207-6219. Go to original source... Go to PubMed...
  8. Nestrašil I. Neurologické projevy systémových maligních nádorů. Neurol. praxi 2005; 1: 21-24.
  9. Nguyen T, DeAngelis L. Treatment od Brain metastases, J Support Oncol 2004; 2(5): 405-416. Go to PubMed...
  10. Nieder C, Grosu AL, Astner ST, Thamm R, Molls M. Integration of chemotherapy into current treatment strategies for brain metastases from solid tumors. Radiat Oncol. 2006; 1: 19. Go to original source... Go to PubMed...
  11. Rakesh R, Patel and Minesh P. Mehta, Targeted Therapy for Brain Metastases: Improving the Therapeutic Ratio, Clin Cancer Res 2007; 13(6): 1675-1683. Go to original source... Go to PubMed...
  12. Šimonová G, Liščák R. Mozkové metastázy, Radiochirugie gama nožem, Grada publishing a.s. 2009: 151-164.
  13. Šimonova G, Liščák R. Radiosurgery in treatment of malignant brain tumors, Expert Rev Anticancer Ter, 2003; 3(6): 879-890. Go to original source... Go to PubMed...
  14. Šlampa P, Petera J, Abrahámová J, Cvek J, Cwiertka K, Čelakovský P, Čoupek P, Dolečková M, Doležal J, Doležel M, Doleželová-Horová H, Dvořák J, Dvořák P, Fadrus P, Feltl D, Frencl L, Fínek J, Honová H, Hübnerová P, Hynková L, Katolická J, Kordač P, Kovařík J, Králová D, Kubecová M, Kubeš J, Kvěch J, Macháňová M, Malinová B, Novotný T, Novotný J, Odrážka K, Ondrová B, Pacík D, Pála M, Pospíšil P, Princ D, Přibylová O, Rovný A, Růžičková J, Soumarová R, Sovadinová-Košťáková Š, Stankušová H, Stejskal J, Strzondala W, Syptáková B, Šeneklová Z, Šimonová G, Vaculíková M, Vošmik M, Zouhar M, Zoul Z. Radiační onkologie, Galén, Karolinum 2007: 381-383, 421-422.
  15. Vodvářka P. Radioterapie a chemoterapie zhoubných nádorů centrálního nervového systému, Neurol. praxi 2003; 5: 242-248.




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