Neurol. praxi. 2012;13(1):22-25

Neuromuscular disorders in thyroid disease

MUDr.Radim Mazanec, Ph.D., MUDr.Tomáš Nedělka, doc.MUDr.Martin Bojar, CSc.
Neurologická klinika 2. lékařské fakulty UK a FN v Motole, Praha

Thyroid gland dysfunction is beside diabetes mellitus the most common endocrinopathy. Both hypothyroidism and hyperthyroidism

may cause signs and symptoms of neuromuscular dysfunction. Hypothyroidism is associated with clinical neuromuscular features in

79 % and hyperthyroidism in 67 % patients. Proximal myopathy, sensorimotor axonal neuropathy and carpal tunnel syndrome are the

most common disorders in hypothyroidism. Hyperthyroidism (Graves Basedow disease) may cause hyperthyroid myopathy, thyrotoxic

periodic paralysis and thyroid-associated ophtalmopathy. Peripheral sensorimotor neuropathy is rare. Neuromuscular symptoms and

signs usually recover completely when thyroid gland dysfunction is corrected.

Keywords: electromyography, endocrine myopathy, Graves ophtalmopathy, peripheral neuropaty, thyreopathy

Published: February 14, 2012  Show citation

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Mazanec R, Nedělka T, Bojar M. Neuromuscular disorders in thyroid disease. Neurol. praxi. 2012;13(1):22-25.
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