Neurol. praxi. 2012;13(6):333-335

Marijuana and epilepsy: myth and facts

MUDr.Ivana Tyrlíková

Univerzitní centrum pro epilepsii, 1. neurologická klinika, FNsP u sv. Anny, Brno

Marijuana contains more than 480 various chemicals. Cannabinoids, which influence neurotransmission and probably modify brain

plasticity, attract the most interest. This effect of individual cannabinoids is still utilized in treatment of vomiting and nausea, especially

with cancer patients. Existing experimental treatments with epilepsy have ambiguous results. Results of many case studies have shown

a reduction of seizure frequency, whereas other studies have shown an increase in it. One study has proved the protective effect of marijuana

in the new onset of epileptic seizures. Nevertheless, this study and other case studies apply to the marijuana herb rather than

individual chemicals. On the other hand, one controlled study has shown a positive effect of a selected cannabinoid called cannabidiol

on seizure frequency. Some positive results point out the necessity of systematic and controlled research of the effect of individual

cannabinoid chemicals in controlled dosages, rather than (or instead of) experimental use of the whole herb which varies in content

and quantity of individual cannabinoids.

Keywords: epilepsy, marijuana, treatment

Published: December 1, 2012  Show citation