Neurol. praxi. 2013;14(6):297-301

Assessment of cognitive function in early diagnosis of Alzheimer’s disease

Mgr.Tomáš Nikolai1,2,3, MUDr.Martin Vyhnálek2,3, Mgr.Eva Literáková3, Hana Marková4, doc.MUDr.Jakub Hort, Ph.D.2,3
1 Centrum klinických neurověd a Neurologická klinika 1. LF UK a VFN v Praze
2 Kognitivní centrum, Neurologická klinika, UK v Praze, 2. LF a FN v Motole, Praha
3 Mezinárodní centrum klinického výzkumu, Fakultní nemocnice u sv. Anny v Brně
4 Katedra psychologie, Filozofická fakulta Univerzity Karlovy v Praze

Cognitive assessment in the diagnostics of Alzheimer’s disease (AD) comprises one of the key diagnostic procedures. Along with the

change in diagnostic criteria for AD, the accent has been shifted into still earlier diagnostics of cognitive impairment with a central focus

on the mild cognitive impairment due to AD. Cognitive screening tests represent a useful estimate of general cognitive function; however,

neuropsychological assessment is necessary for a complex analysis. The objective of neuropsychological assessment is detecting clinically

significant decrease of cognitive function, as well as profiling cognitive function for the purpose of differential diagnosis. Authors

summarize the form and alternatives of cognitive assessment in early stages of AD with a focus on stage of MCI, and recommend methods

of assessment of cognitive function for clinical praxis.

Keywords: Alzheimer’s disease, mild cognitive impairment, neuropsychological assessment, diagnostic criteria

Published: December 1, 2013  Show citation

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Nikolai T, Vyhnálek M, Literáková E, Marková H, Hort J. Assessment of cognitive function in early diagnosis of Alzheimer’s disease. Neurol. praxi. 2013;14(6):297-301.
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