Neurol. praxi. 2014;15(3):141-145

Ideopathic „benign” focal epilepsies in childhood

MUDr. Ondřej Horák, doc. MUDr. Hana Ošlejšková, Ph.D.
Centrum pro epilepsie Brno, Klinika dětské neurologie LF MU a FN Brno

Benign focal epilepsies (BFE) are one of the most frequent epilepsies in childhood. They are usually described as an epileptic spectrum, whose nosologic units have the same pathogenetic base, may show blurry boundaries among them and may convert during the time. Besides well-known epilepsy with centro-temporal spikes or Panayiotopoulos syndrome, there are new recently defined syndromes, completing the spectrum. Nowadays, the molecular genetic background of BFE is the largest area of interest as well as the research of psychologic-psychiatric comorbidities, which acquire searching for answer the question: Are the benign focal epilepsies really benign? encephalopaties.

Keywords: benign focal epilepsies, benign epilepsy with centro-temporal spikes, Panayiotopoulos type, atypical evolution, epileptic

Published: June 9, 2014  Show citation

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Horák O, Ošlejšková H. Ideopathic „benign” focal epilepsies in childhood. Neurol. praxi. 2014;15(3):141-145.
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    References

    1. Bray PF, Wiser WC. Evidence for a genetic etiology of temporal central abnormalities in focal epilepsy. N Engl J Med 1964; 271: 926-933. Go to original source... Go to PubMed...
    2. Capovilla G, Beccaria F. Benign partial epilepsy in infancy and early childhood with vertex spikes and waves during sleep: a new epileptic form. Brain Dev 2000; 2: 93-99. Go to original source... Go to PubMed...
    3. Caraballo R, Cersósimo R, Espeche A, Fejerman N. (2003a) Benign familial and non-familial infantile seizures: a study of 64 patients. Epileptic disorder 2003; 5: 45-49.
    4. Caraballo R, Cersosimo R, Medina C, Fejerman N. Panayiotopoulos-type benign childhood occipital epilepsy: a prospective study. Neurology 2000; 55: 1096-1100. Go to original source... Go to PubMed...
    5. Caraballo R, Fejerman N, Dalla Bernardina. (2003b) Epileptic spasms in cluster without hypsarytmia in infancy. Epileptic Disorder 2003; 5(2): 109-113.
    6. Engel J Jr. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: Report of ILAE Task Force on Classifcation and Terminology. Epilepsia 2001; 42: 796-803. Go to original source... Go to PubMed...
    7. Engel J. Report of the ILAE Classification Core Group. Epilepsia 2006; 47(9): 1558-1568. Go to original source... Go to PubMed...
    8. Fejerman N, Caraballo RH, Tenenbaum S. Atypical evolutions of Benign Localization-related Epilepsies in Children. Are they predictable? Epilepsia 2000; 41: 380-390. Go to original source... Go to PubMed...
    9. Fejerman N, Caraballo RH. Benign focal epilepsies in Infancy, Childhood and Adolescence. John Libbey Eurotext, UK, 2007: 3-11, 15-25, 31-44, 63-71, 77-165.
    10. Ferrie CD, Caraballo RH, Covanis A. Panayiotopoulos syndrome: a consensus view. Develop Med Child Neurol Mar 2006; 48(3): 236-240. Go to original source... Go to PubMed...
    11. Fukuyama Y. Borderland of epilepsy with special reference to febrile convulsions and so-called infantile convulsions. Seishin-Igaku (Clin Psychiatry) 1963; 5: 211-223.
    12. Germano E, Gagliano A, Magazu A. Benign childhood epilepsy with occipital paroxysms: neuropsychological findings. Epilepsy Res 2005; 64(3): 137-150. Go to original source... Go to PubMed...
    13. Gibbs EL, Gibbs FA. Good prognosis of mid-temporal epilepsy. Epilepsia 1960; 1: 448-453. Go to original source... Go to PubMed...
    14. Gastaut Y. Un élément déroutant de la séméiologie électroencéphalographique: les pointes prérolandiques sans signification focale. Rev Neurol (Paris) 1952; 87: 488-490.
    15. Heijbel J, Blom S, Rasmuson M. Benign epilepsy of childhood with centrotemporal EEG foci: a genetic study. Epilepsia 1975; 16: 285-293. Go to original source... Go to PubMed...
    16. Hommet C, Billard C, Motte J. Cognitive function in adolesctents and young adults in complete remisson from benign childhood epilepsy with centrotemporal spikes. Epileptic Disord 2001; 3(4): 207-216. Go to PubMed...
    17. Chahine L, Mikati M. Bening pediatric localization-related epilepsies. Part II. Syndromes in childhood. Epileptic Disord 2006; 8(4): 243-258. Go to PubMed...
    18. Chinon C, Raynaud C, Maziere B. Changes in regional cerebral blood flow during brain maturation in children and adolescents. Journal of Nuclear Medicine 1992; 33(5): 696-703.
    19. Chugani HT. A critical period of brain development: studies of cerebral glucose utilization with PET. Preventive Medicine 1998; 27(2): 184-188. Go to original source... Go to PubMed...
    20. Lombrosso CT. Sylvian seizures and midtemporal spike foci in children. Arch Neurol 1967; 17: 52-59. Go to original source... Go to PubMed...
    21. Malaffose A, Beck C, Bellet H. Benign infantile familial convulsions are not alelic form of the benign familial neonatal convulsion gene. Ann Neurol 1994; 35: 479-482. Go to original source... Go to PubMed...
    22. Matsufuji H, Ichiyama T, Isumi H, Furukawa S. Low-dose carbamazepine therapy for benign infantile convulsions. Brain Dev 2005; 27: 554-557. Go to original source... Go to PubMed...
    23. Minami T, Gondo K, Yamamoto T. Magnetoecephalografic analysis of rolandic discharges in benign childhood epilepsy. Clin Electroencephalogr 1996; 39(3): 326-334. Go to original source...
    24. Neubauer BA, Fiedler B, Himmelein B. Centrotemporal spikes in families with rolandic epilepsy: linkage to chromosom 15q14. Neurology 1998; 51(6): 1608-1612. Go to original source... Go to PubMed...
    25. Okumura A, Watanabe K, Negoro T. Long-term follow-up of patients with benign partial epilepsy in infancy. Epilepsia 2006; 47: 181-185. Go to original source... Go to PubMed...
    26. Ottman R, Lipton RB. Is the comorbidity of epilepsy and migraine due to a shared genetic susceptibility? Neurology 1196; 47(4): 918-924. Go to original source... Go to PubMed...
    27. Panayiotopoulos CP. Panayiotopoulos syndrome: A common and benign childhood epileptic syndrome. London. John Libbey, 2002.
    28. Papavasiliou A, Mattheou D, Bazigou H, Kotsalis C, Paraskevoulakos E. Written language skills in children with benign childhood epilepsy with centro-temporal spikes. Epilepsy Behav 2005; 6(1): 50-58. Go to original source... Go to PubMed...
    29. Steinlein OK, Neubauer BA, Sander T. Mutation analysis of the potassium chloride cotransporter KCC3 in rolandic and idiopathic generalized epilepsy. Epilepsy Res 2001; 44(2-3): 191-195. Go to original source... Go to PubMed...
    30. Verrotti A, Latini G, Trotta D. Typical and atypical rolandic epilepsy in childhood: a follow-up study. Pediatr Neurol 2002; 26(1): 26-29. Go to original source... Go to PubMed...
    31. Yoshinaga H, Koutroumanidis M, Shirasawa A, Kikumoto K, Ohtsuka Y, Oka E. Dipole analysis in Panayiotopoulos syndrome. Brain Dev 2005; 27: 46-52. Go to original source... Go to PubMed...

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