Neurol. praxi. 2015;16(1):44-47
Effect of LPG-endermotherapy on skin changes resulting from long-term treatment with glatiramer acetate
- 1 Dermatovenerologické oddělení, Oblastní nemocnice Kladno
- 2 Neurologická klinika 2. LF UK a FN Motol, Praha
Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system (CNS). Early initiation of treatment can slow down the whole process. The article deals with local adverse effects at the injection site when using glatiramer acetate (GA) – Copaxone®, and, in particular, with interfering with the local response by means of the LPG-endermotherapy technique. It is a unique technology that was developed based on personal experience of the founder and author, Mr. Louis Paul Guitay (LPG). Endermotherapy is mechanical stimulation of sensitive tissue with a special lift head during which activation of fibroblasts and stimulation of both the lymphatic and blood systems occur, leading to collagen and elastin neoformation.
Keywords: panniculitis, lipoatrophy, glatiramer acetate, LPG-endermotherapy
Published: January 26, 2015 Show citation
References
- Braun-Falco O, Plewig G, Wolff HH. Dermatológia a venerológia, Martin: Osveta 2001: 706-722.
Go to original source... - Štork J, et al. Dermatovenerologie, 2. vyd., Praha: Galén 2013: 245-249.
- Šťáva Z, Jirásek L, Schwank R, Trapl J. Dermatovenerologie, Praha Avicenum 1977: 267-268.
- Jarkovský J, Malúšková D. Podklady pro hodnocení efektivity ošetření LPG endermologie u pacientů při injekční léčbě Copaxonem(R), Institut biostatistiky a analýz, Lékařská a Přírodovědecká fakulta, Masarykova Univerzita Brno I/2014.
- Aharoni R. The mechanism of action of glatiramer acetate in multiple sclerosis and beyond. Autoimmun Rev. 2013 Mar; 12(5): 543-553. doi Go to original source...
Go to PubMed... - Lebrun C, Mondot L, Bertagna M, Calleja A, Cohen M. Endermology: a treatment for injection-induced lipoatrophy in multiple sclerosis patients treated with sub cutaneous glatiramer acetate. Clin Neurol Neurosurg. 2011 Nov; 113 (9): 721-4. doi:10.1016/j.clineuro.2011.07.012. Epub 2011 Aug 11. PubMed PMID: 21839580. Go to original source... Go to PubMed...