Neurol. praxi. 2015;16(2):108-110
Encephalitis of unclear origin with suspected Epstein-Barr virus aetiology
- Neurologické oddelenie NsP, Spišská Nová Ves
The present case report describes a 50-year-old female patient two years after kidney transplantation on permanent immunosuppressive therapy who suddenly developed reversible dementia syndrome. Given the 14-3-3 protein positivity and a history of organ transplant from an unknown donor, a diagnosis of prion infection was taken into consideration, among other things. The subsequent reversal of the clinical course with a relatively sudden abatement of symptoms supported the diagnosis of atypically proceeding neuroinfection without demonstration of the aetiological agent. During follow-up, the patient experienced recurrence of symptoms a month later, with imaging and laboratory testing performed showing encephalitis of unclear origin, most likely Epstein-Barr virus encephalitis.
Keywords: encephalitis, Epstein-Barr virus, 14-3-3 protein
Published: May 1, 2015 Show citation
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