Neurol. praxi. 2015;16(3):144-148

Errors and mistakes in diagnosing multiple sclerosis

MUDr. Jiří Piťha
MS centrum při Neurologickém odděleni KZ a.s. – Nemocnice Teplice o. z., Teplice

The late establishment of the diagnosis of multiple sclerosis results in delay in treatment initiation, affecting the course of the disease, and thus in poorer prognosis. In the case of a false positive diagnosis, in addition to funds being expended inappropriately, the patient is exposed to the risk of adverse drug effects. Particular attention has to be paid to patient history data analysis, proper assessment of clinical evaluation, and realistic interpretation of auxiliary examinations.

Keywords: multiple sclerosis, diagnosis, treatment, errors, mistakes

Published: June 26, 2015  Show citation

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Piťha J. Errors and mistakes in diagnosing multiple sclerosis. Neurol. praxi. 2015;16(3):144-148.
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References

  1. Abraira V, Alvarez-Cerme?o JC, Arroyo R, Cámara C, Casanova B, Cubillo S, de Andrés C, Espejo C, Fernández O, Ferrer J, Figueredo MA, García-Merino A, García-Sánchez MI, García-Trujillo JA, Gómez M, González-Oria C, Gosis A, Izquierdo G, Jímenez J, López-Trascasa M, Montalbán X, Moreno MJ, Mu?oz D, Nu?ez V, Muriel A, Navarro J, Olascoaga J, Oreja-Guevara C, Prada A, Ramil E, Ramo-Tello C, Rodríguez C, Rodríguez E, Rodríguez-Frías F, Rodríguez-Antigüedad A, Rodríguez-Molina JJ, Ruiz E, Saiz A, Sarasola E, Simó M, Yagüe J, Villar LM. Utility of oligoclonal IgG band detection for MS diagnosis in daily clinical practice. J Immunol Methods 2011; 371(1-2): 170-173. Go to original source... Go to PubMed...
  2. Antel J, Antel S, Caramanos Z, Arnold DL, Kuhlmann T. Primary progressive multiple sclerosis: part of the MS disease spectrum or separate disease entity? Acta Neuropathol 2012; 123 (5): 627-638. Go to original source... Go to PubMed...
  3. Bourahoui A, De Seze J, Guttierez R, CSF isoelectrofocusing in a large cohort of MS and other neurological diseases. Eur J Neurol 2004; 11(8): 525-529. Go to original source... Go to PubMed...
  4. Kuhle J, Disanto G, Dobson R, Adiutori R, Bianchi L, Topping J, Bestwick J, Meier UC, Marta M, Costa GD, Runia T, Evdoshenko E, Lazareva N, Thouvenot E, Iaffaldano P, Direnzo V, Khademi M, Piehl F, Comabella M, Sombekke M, Killestein J, Hegen H, Rauch S, D'Alfonso S, Alvarez-Cerme?o J, Kleinová P, Horáková D, Roesler R, Lauda F, Llufriu S, Avsar T, Uygunoglu U, Altintas A, Saip S, Menge T, Rajda C, Bergamaschi R, Moll N, Khalil M, Marignier R, Dujmovic I, Larsson H, Malmestrom C, Scarpini E, Fenoglio C, Wergeland S, Laroni A, Annibali V, Romano S, Martínez A, Carra A, Salvetti M, Uccelli A, Torkildsen ?, Myhr K, Galimberti D, Rejdak K, Lycke J, Frederiksen J, Drulovic J, Confavreux C, Brassat D, Enzinger C, Fuchs S, Bosca I, Pelletier J, Picard C, Colombo E, Franciotta D, Derfuss T, Lindberg R, Yaldizli Ö, Vécsei L, Kieseier B, Hartung H, Villoslada P, Siva A, Saiz A, Tumani H, Havrdová E, Villar L, Leone M, Barizzone N, Deisenhammer F, Teunissen C, Montalban X, Tintoré M, Olsson T, Trojano M, Lehmann S, Castelnovo G, Lapin S, Hintzen R, Kappos L, Furlan R, Martinelli V, Comi G, Ramagopalan S, Giovannoni G. Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study. Mult Scler 2015 Feb 13. Go to original source... Go to PubMed...
  5. Miller D, Chard D, Ciccarelli O. Clinically isolated syndromes. Lancet Neurol 2012; 11: 157-169. Go to original source... Go to PubMed...
  6. Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, Fujihara K, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Montalban X, O'Connor P, Sandberg-Wollheim M, Thompson AJ, Waubant E, Weinshenker B, Wolinsky JS. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 2011; 69(2): 292-302. Go to original source... Go to PubMed...
  7. Roohani P, Emiru T, Carpenter A, Luzzio C, Freeman J, Scarberry S, Gary G, Davidson L, Parry, G. Late onset multiple sclerosis: Is it really late onset? Mult Scler Relat Disord 2014; 3(4): 444-449. Go to original source... Go to PubMed...
  8. Solomon AJ, Klein EP, Bourdette D. "Undiagnosing" multiple sclerosis: the challenge of misdiagnosis in MS. Neurology 2012; 78(24): 1986-1991. Go to original source... Go to PubMed...
  9. Vaněčková M, Seidl Z. Radiodiagnostický algoritmus roztroušené sklerózy. Neurol. praxi 2013; 14 (Suppl. C): 9-13.




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