Neurol. praxi. 2016;17(6):397-400

Levodopa-carbidopa intestinal gel in the treatment of Parkinson’s disease - a case report

MUDr. Aleš Kopal
Neurologická klinika, Pardubická nemocnice, Nemocnice Pardubického kraje a.s.

Continuous administration of levodopa-carbidopa intestinal gel is a treatment option for motor fluctuations and dyskinesias in advanced Parkinson‘s disease. A suspension of levodopa-carbidopa is delivered in an aqueous gel from a casette reservoir by an infusion pump via percutaneous endoscopic gastrostomy with jejunal extension tube. Continuous administration leads to reduced variability in plasma-levodopa concentrations and subsequently to decreased motor fluctuations and dyskinesias. A case report of 56 year old woman with history of Parkinson‘s disease for 16 years and significant reduction of motor complications due to administration of levodopa-carbidopa intestinal gel for 6 years is presented.

Keywords: Parkinson’s disease, levodopa-carbidopa intestinal gel, motor fluctuations and dyskinesias

Published: December 1, 2016  Show citation

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Kopal A. Levodopa-carbidopa intestinal gel in the treatment of Parkinson’s disease - a case report. Neurol. praxi. 2016;17(6):397-400.
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