Neurol. praxi. 2018;19(1):11-15 | DOI: 10.36290/neu.2017.027

Pediatric epileptosurgery – special considerations and current trends

MUDr. Ondřej Horák
Klinika dětské neurologie LF MU a FN Brno, Centrum pro epilepsie Brno

Possibilities of modern epilepsy surgery offer help to most patients with drug-resistant epilepsy. The new surgical techniques,extending arsenal of epilepsy surgery procedures and still increasing quality of presurgical evaluation enable successful surgicalsolution of more complicated patients, not only in adulthood, but also in childhood. There is a clear worldwide trend, not onlyin increase of resections in MRI-nonlesional and extratemporal patients, but also in proportional growth of epilepsy surgery approachesin childhood, including the youngest age bracket. The aim of epilepsy surgery in children is not merely seizure reduction,but also arrangement as most favourable psycho-motor development as possible. The key for this achievement is chiefly the rightand well-timed selection of eligible candidates, where the timing is just crucial. The following text refers to specifics of pediatricepileptology, affecting the planning, management and ultimately outcome of pediatric epilepsy surgery.

Keywords: epilepsy, epilepsy surgery, drug-resistance, neuroplasticity

Received: May 23, 2017; Accepted: June 14, 2017; Published: March 1, 2018  Show citation

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Horák O. Pediatric epileptosurgery – special considerations and current trends. Neurol. praxi. 2018;19(1):11-15. doi: 10.36290/neu.2017.027.
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References

  1. Barba C, Specchio N, Guerrini R, Tassi L, De Masi S, Cardinale F, Pellacani S, De Palma L, Battaglia D, Tamburrini G, Didato G, Freri E, Consales A, Nozza P, Zamponi N, Cesaroni E, Di Gennaro G, Esposito V, Giulioni M, Tinuper P, Colicchio G, Rocchi R, Rubboli G, Giordano F, Lo Russo G, Marras CE, Cossu M. Increasing volume and complexity of pediatric epilepsy surgery with stable seizure outcome between 2008 and 2014: A nationwide multicenter study. Epilepsy and Behavior 2017; 75: 151-157. Go to original source... Go to PubMed...
  2. Baumgartner JE, Blout JP, Blauwblomme T, Chandra PS. Technical descriptions of four hemispherectomy approaches: From the Pediatric Epilepsy Surgery Meeting at Gothenburg 2014. Epilepsia 2017; 58(Suppl. 1): 46-55. Go to original source... Go to PubMed...
  3. Brázdil M. Proměny epileptochirurgie ve 21. století. Neurol. praxi 2015; 16(2): 77-79.
  4. Carpay HA, Arts WF, Geerts AT, Stroink H, Brouwer OF, Boudenwyn Peters AC, Van Donselaar CA. Epilepsy in childhood: an audit of clinical practice. Arch Neurol 1998; 55: 668-673. Go to original source... Go to PubMed...
  5. Cross JH, Arzimanoglou A, Kahane P, Holthauser H, Mathern G, Gaillard WD, Jayakar P. Epilepsy surgery in children: Time is critical. In Pediatric Epilepsy Surgery, John Libbey Eurotext 2016.
  6. Cross JH, Jayakar P, Nordli D, Delalande O, Duchowny M, Wiesser HG, Guerrini R, Mathern GW. Proposed criteria for referral and evaluation of children with epilepsy for surgery: recommendations of the Subcommission of Pediatric Epilepsy Surgery. Epilepsia 2006; 47: 952-959. Go to original source... Go to PubMed...
  7. D'Argenzio LD, Colonnelli MCh, Harrison S, Jacques TS, Harkness W, Vargha-Khadem F, Scott RC, Cross JH. Cognitive outcome after extratemporal epilepsy surgery in childhood. Epilepsia 2011; 52(11): 1966-1972. Go to original source... Go to PubMed...
  8. Davidson S, Falconer MA. Outcome of surgery in 40 children with temporal-lobe epilepsy. Lancet 1975; 1: 1260-1263. Go to original source... Go to PubMed...
  9. Eltze C, Chong WK, Harding B, Cross JH. Focal cortical dysplasia in infants; some MRI lesions almost disappear with maturation of myelination. Epilepsia 2005; 46: 1988-1922. Go to original source... Go to PubMed...
  10. Harvey AS, Cross JH, Shinnar S, Mathern GW. Seizure syndromes, etiologies and procedures in paediatric epilepsy: A 2004 International Survey. Epilepsia 2008; 49: 146-155. Go to original source... Go to PubMed...
  11. Hertz-Pannier L, Chiron C, Jambagué I, Renaux-Kieffer V, Van se Moortele PF, Delalande O, Fohlen M, Brunelle F, Le Bihan D. Late plasticity for language in a child's non-dominant hemisphere: a pre and post surgery fMRI study. Brain 2002; 125: 361-372. Go to original source... Go to PubMed...
  12. Holland KD, Glauser TA. Response to carbamazepine in children with newly diagnosed partial onset epilepsy. Neurology 2007; 69(6): 596-599. Go to original source... Go to PubMed...
  13. Jehi L, Friedman D, Carlson Ch, Cascino G, Dewar S, Elger Ch, Engel J, Knowlton R, Kuzniecky R, McIntosh A, O'Brian TJ, Spencer D, Sperling MR, Worrel G, Bingaman B, Gonzales-Martinez J, Doyle W, French J. The evolution of epilepsy surgery between 1991 and 2011 in nine major epilepsy centers across the United States, Germany, and Australia. Epilepsie 2015; 56(10): 1526-1533. Go to original source... Go to PubMed...
  14. Kellermann TS, Wagner JL, Smith G, Karia S, Eskandari R. Surgical Management of Pediatric Epilepsy: Decision-Making and Outcomes. Pediatr Neurol 2016; 64: 21-31. Go to original source... Go to PubMed...
  15. Krynauw RA. Infantile hemiplegia treated by removal on one cerebral hemisphere. J Neurol Neurosurg Psychiatry 1950; 13: 243-267. Go to original source... Go to PubMed...
  16. Kwan P, Arzimanoglou A, Berg AT, Brodie MJ, Allen Hauser W, Mathern G, Moshé SL, Perucca E, Wiebe S, French J. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 2010; 51: 1069-1077. Go to original source... Go to PubMed...
  17. Lamberink HJ, Boshuisen K, Van Rijen PC, Gosselaar PH, Braun KPJ. Changing profiles of pediatric epilepsy surgery candidates over time: A natiowide single-center experience from 1990 to 2011. Epilepsia 2015; 56(5): 717-725. Go to original source... Go to PubMed...
  18. McKenzie K. The present status of patients who had the right cerebral hemisphere removed. JAMA 1938; 111: 168-183.
  19. Simasathien T, Najm I, Gupta A, Jehi L, Vadera S, Bingaman W. Improved Outcomes with Earlier Surgery for Intractable Frontal Lobe Epilepsy. Ann Neurol 2013; 73(5): 646-654. Go to original source... Go to PubMed...
  20. Skirrow C, Cross JH, Cormack F, Harkness W, Vargha-Khadem F, Baldeweg T. Long-term outcome after temporal lobe surgery in childhood; Intellectual gains are correlated with brain volume changes. Neurology 2011; 76: 1330-1337. Go to original source... Go to PubMed...




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