Neurol. praxi. 2020;21(1):68-70 | DOI: 10.36290/neu.2020.013
Autoimmune encephalitis? Not. False positivity of anti-NMDA antibodies in patient with Creutzfeldt-Jacob disease
- 1 I. neurologická klinika, LF MU, FN u sv. Anny v Brně
- 2 Středoevropský technologický institut (CEITEC), Brno
Anti-NMDA encephalitis is one of many types of autoimunne encephalitis (AIE), about which we are thinking during diagnostic process even more in these days. Typical symptoms of AIE are loss of memory, epileptic seizures and psychiatric symptoms. During diagnostic process is important to find positivity of antibodies, in the case of anti-NMDA encephalitis there are antibodies against N-methyl-D-aspartate receptors, which are placed on almost all neurons in the brain and spinal cord. Early diagnosis and treatment of this disease is an important prognostic factor. However there are some cases, in which there is no association between anti-NMDA antibodies and autoimunne encephalitis, as we can see in the following case report.
Keywords: anti-NMDA encephalitis, autoimunne encephalitis.
Received: February 22, 2020; Revised: February 22, 2020; Accepted: February 22, 2020; Prepublished online: February 22, 2020; Published: March 30, 2020 Show citation
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