Neurol. praxi. 2020;21(5):390-394 | DOI: 10.36290/neu.2020.016

Epidemiology of Parkinson's disease

MUDr. Tereza Bartoníková¹, doc. MUDr. Kateřina Menšíková, Ph.D.¹, prof. MUDr. Vladimír Janout, CSc.², prof. MUDr. Petr Kaňovský, CSc.¹

¹ Neurologická klinika Fakultní nemocnice a Lékařské fakulty Univerzity Palackého v Olomouci

² Centrum vědy a výzkumu, Fakulta zdravotních věd Univerzity Palackého v Olomouci

Idiopathic (sporadic) Parkinson's disease (PD) is one of the most frequent neurodegenerative disorders. The disease has heterogenous pfenotype and origin: both endogenous (genetic) and exogenous (enviromental) factors probably participate on manifestations of the PD and many other factors are involved. However, the exact pathophyziological cause has not been indentified yet. Therefore it is exceptionally important to collect all data which could help understanding the development of the Parkinson's disease. The epidemiological data can expose factors which can be further experimentally verified. It is essential to point out that relevant data about prevalence and incidence of PD are relatively rare. Just few epidemiological studies has been conducted yet using validated methods and if so, just small groups in geographically restricted areas were examined and other studies were contucted in regions with endemic incidence od parkinsonism. However, available studies suggest that the prevalence of PN and neurodegenerative parkinsonism increases with age, estimated incidence is in the range of 10-50 cases per 100 000 per year, and the probable prevalence rate is 100-300 patients per 100 000 inhabitants.

Keywords: Parkinson´s disease, epidemiology, incidence, prevalence.

Received: December 4, 2019; Revised: March 12, 2020; Accepted: March 12, 2020; Prepublished online: March 12, 2020; Published: November 11, 2020  Show citation