Neurol. praxi. 2021;22(5):410-415 | DOI: 10.36290/neu.2021.083

Migraine and comorbidities

doc. MUDr. Vladimír Nosáµ, PhD., FESO, doc. MUDr. ©tefan Sivák, PhD.
Neurologická klinika JLF UK a UNM, Martin

Migraine is associated with several comorbidities. The most important comorbidities are mentioned. Basic supposed pathomechanisms are shortly discussed together with specific migraine treatment with regards on present comorbidity.

Keywords: migraine, comorbidities, depression, cardiovascular diseases.

Received: August 5, 2021; Revised: September 21, 2021; Accepted: October 21, 2021; Prepublished online: October 21, 2021; Published: November 8, 2021  Show citation

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Nosáµ V, Sivák ©. Migraine and comorbidities. Neurol. praxi. 2021;22(5):410-415. doi: 10.36290/neu.2021.083.
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References

  1. Adelborg K, Szépligeti SK, Holland-Bill L, Ehrenstein V, Horváth-Puhó E, Henderson WV. Migraine and risk of cardiovascular diseases: Danish population based matched cohort study. BMJ 2018; 360: k96. Go to original source... Go to PubMed...
  2. Bigal ME, Lipton RB. The epidemiology, burden, and comorbidities of migraine. Neurologic Clinics 2009; 27: 321-334. doi: 10.1016/j.ncl.2008.11.011. Go to original source... Go to PubMed...
  3. Bonafede M, Sapra S, Shah N, Tepper S, Cappel K, Desai P. Direct and indirect healthcare resource utilization and costs among migraine patients in the United States. Headache 2018; 58(5): 700-14. Go to original source... Go to PubMed...
  4. Breslau N, Schultz L, Lipton R, Peterson E, Welch KM. Migraine headaches and suicide attempt. Headache 2012; 52(5): 723-731. Go to original source... Go to PubMed...
  5. Buse DC, Loder EW, Gorman JA, Stewart WF, Reed ML, Fanning KM, Serrano D, Lipton RB. Sex differences in the prevalence, symptoms, and associated features of migraine, probable migraine and other severe headache: results of the American Migraine Prevalence and Prevention (AMPP) Study. Headache 2013; 53(8): 1278-99. Go to original source... Go to PubMed...
  6. Buse, DC, Reed, ML, Fanning, KM, Bostic R, Dodick DW, Schwedt TJ, Munjal S, Singh P, Lipton RB. Comorbid and co-occurring conditions in migraine and associated risk of increasing headache pain intensity and headache frequency: results of the migraine in America symptoms and treatment (MAST) study. J Headache Pain 2020; 1: 23. Go to original source... Go to PubMed...
  7. Buse DC, Manack A, Serrano D, Turkel C, Lipton RB. Sociodemographic and comorbidity pro - files of chronic migraine and episodic migraine sufferers. J Neurol Neurosurg Psychiatry. 2010; 81(4): 428-32. Go to original source... Go to PubMed...
  8. Buse DC, Silberstein SD, Manack AN, Papapetropoulos S, Lipton RB. Psychiatric comorbidities of episodic and chronic migraine. J Neurol. 2012; 260(8): 1960-9. Go to original source... Go to PubMed...
  9. Didriksen M, Hansen TF, Thørner LW, Burgdorf KS, Erikstrup C, Pedersen OB, Paarup HM, Nielsen KR, Hjalgrim H, Sørensen E, Ullum H. Restless legs syndrome is associated with increased risk of migraine. Cephalalgia Reports. 2018; 1: 1-7. Go to original source...
  10. GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 2016; 388: 1474-547X.
  11. Gudmundsson LS, Thorgeirsson G, Sigfusson N, Sigvaldason H, Johannsson M. Migraine patients have lower systolic but higher diastolic blood pressure compared with controls in a population-based study of 21,537 subjects. The Reykjavik Study. Cephalalgia 2006; 26(4): 436-44. doi: 10.1111/j.1468-2982.2005.01057.x. PMID: 16556245 Go to original source... Go to PubMed...
  12. Hamel E. Serotonin and migraine: biology and clinical implications. Cephalalgia 2007; 27(11): 1293-1300. Go to original source... Go to PubMed...
  13. Heckman BD, Holroyd KA, Himawan L, O'Donnell FJ, Tietjen G, Utley C, Stillman M. Do psychiatric comorbidities influence headache treatment outcomes? Results of a naturalistic longitudinal treatment study. Pain 2009; 146(1-2): 56-64. Go to original source... Go to PubMed...
  14. Husain F, Pardo G, Rabadi M. Headache and Its Management in Patients With Multiple Sclerosis. Curr Treat Options Neurol. 2018; 20(4): 10. Go to original source... Go to PubMed...
  15. Lipton RB, Manack Adams A, Buse DC, Fanning KM, Reed ML. A comparison of the chronic migraine epidemiology and outcomes (CaMEO) study and American migraine prevalence and prevention (AMPP) study: demographics and headache - related disability. Headache 2016; 56(8): 1280-9. Go to original source... Go to PubMed...
  16. Kister I, Caminero AB, Monteith AB, Soliman A, Bacon TE, Bacon JH, Kalina JT,Inglese M, Herbert J, Lipton RB. Migraine is comorbid with multiple sclerosis and associated with a more symptomatic MS course. J Headache Pain 2010; 11: 417-425. Go to original source... Go to PubMed...
  17. Liao J, Tian X, Wang H, Xiao Z. Epilepsy and migraine-Are they comorbidity? Epilepsy and migraine-Are they comorbidity? Genes & Diseases 2018; 5(2): 112-118. Go to original source... Go to PubMed...
  18. Lipton RB, Cohen JM, Galic M, Seminerio MJ, Yeung PP, Aycardi E, Bigal ME, Bibeau K, Buse DC. Effects of fremanezumab in patients with chronic migraine and comorbid depression: Subgroup analysis of the randomized HALO CM study. Headache 2021; 61(4): 662-672. Go to original source... Go to PubMed...
  19. Maizels M, Buse DC, Jedynak J, Hand AL, Ford J, Detke H. Changes in Depression and Anxiety in a Randomized, Double-blind, Placebo-controlled Study of Galcanezumab in Adults with Treatment-resistant Migraine: Results from the CONQUER Study (1383) Neurology 2020; 94(Suppl. 15): 1383. Go to original source...
  20. Marino E, Fanny B, Lorenzi C, Pirovano A, Franchini L, Colombo C, Bramanti P, Smeraldi E. Genetic bases of comorbidity between mood disorders and migraine: possible role of serotonin transporter gene. Neurol Sci. 2010; 31(3): 387-391. Go to original source... Go to PubMed...
  21. Moschiano F, D'Amico D, Canavero I, Pan I, Micieli G, Bussone G. Migraine and depression: common pathogenetic and therapeutic ground? Neurol Sci. 2011; 32(Suppl. 1): S85-S88. Go to original source... Go to PubMed...
  22. Natoli JL, Manack A, Dean B, Butler DQ, Turkel CC, Stovner L, Lipton RB. Global prevalence of chronic migraine: a systematic review. Cephalalgia 2009; 30(5): 599-609. Go to original source... Go to PubMed...
  23. Patwardhan MB, Samsa GP, Lipton RB, Matchar DB. Changing physician knowledge, attitudes, and beliefs about migraine: evaluation of a new educational intervention. Headache 2006; 46(5): 732-41. Go to original source... Go to PubMed...
  24. Peroutka SJ, Price SC, Wilhoit TL, Jones KW. Comorbid migraine with aura, anxiety, and depression is associated with dopamine D2 receptor (DRD2) NcoI alleles. Mol Med. 1998; 4(1): 14-21. Go to original source...
  25. Nye BL, Thandani VM. Migraine and Epilepsy: Review of the Literature. Headache: The Journal of Head and Face Pain. 2015; 55: 359-380. Go to original source... Go to PubMed...
  26. Peres MF, Mercante JP, Guendler VZ, Corchs F, Bernik MA, Zukerman E, Silberstein SD. Cephalalgiaphobia: a possible specific phobia of illness. J Headache Pain. 2007; 8(1): 56-59. Go to original source... Go to PubMed...
  27. Sacco S, Ornello R, Ripa P, Tiseo C, Degan D, Pistoia F, Carolei A. Migraine and risk of ischaemic heart disease: a systematic review and meta-analysis of observational studies. Eur J Neurol. 2015; 22(6): 1001-11. Go to original source... Go to PubMed...
  28. Scher AI, Bigal ME, Lipton RB. Comorbidity of migraine. Curr Opin Neurol. 2005; 18(3): 305-10. Go to original source... Go to PubMed...
  29. Tepper S, Broessner G, Buse D, Schwedt T, Strauss E, Zhang F, Picard H, Mikol D. Efficacy of Erenumab for the Treatment of Patients with Episodic Migraine with Depression and/or Anxiety (P4.105) Neurology 2018; 90(Suppl. 15): P4.105. Go to original source...
  30. Tiseo C, Vacca A, Felbush A, Filimonova T, Gai A, Glazyrina T, Hubalek IA, Marchenko Y, Overeem LH, Piroso S, Tkachev A, Martelli P, Sacco S. Migraine and sleep disorders: a systematic review.J Headache Pain. 2020; 21: 126. Go to original source... Go to PubMed...




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