Neurol. praxi. 2022;23(4):336-338 | DOI: 10.36290/neu.2021.057

Neuromyelitis optica imitating astrocytoma

MUDr. Kryštof Švub¹, MUDr. Kamila Revendová^{1, 2}, doc. MUDr. Ondřej Volný, Ph.D.^{1, 2}, MUDr. Pavel Hradílek, Ph.D.^{1, 2}, MUDr. Olga Zapletalová^{1, 2}, RNDr. Pavlína Kušnierová, Ph.D.^{3, 4}, prof. MUDr. Michal Bar, Ph.D.^{1, 2}

¹ Neurologická klinika Fakultní nemocnice Ostrava

² Katedra klinických neurověd, Lékařská fakulta Ostravské univerzity, Ostrava

³ Ústav laboratorní diagnostiky, Fakultní nemocnice Ostrava

⁴ Katedra biomedicínských oborů, Lékařská fakulta, Ostravská univerzita, Ostrava

Our case report presents a 23-year-old young female who was admitted to the Department of Neurology at the University Hospital Ostrava for further investigation of progressive central quadruparesis and a finding of an elongated spindle-shaped lesion with affection of the spinal gray matter in the cervical and rostral thoracic spinal segments on a T2 weighted magnetic resonance imaging. In a differential diagnosis process of a patient with an extensive spinal cord hypersignal lesion on T2 weighted images it is important to take into our diagnostic considerations a diagnosis from the neuromyelitis optica spectrum disorders, and both the anti-aquaporin and anti-myelin oligodendrocyte glycoprotein antibodies should be tested from the serum, so that these patients do not have to undergo a spinal cord surgery due to a misdiagnosis of spinal cord tumour.

Keywords: AQP4-IgG, MOG-IgG, Wingerchuk's diagnostic criteria, myelitis.

Received: June 6, 2021; Revised: July 27, 2021; Accepted: August 10, 2021; Prepublished online: August 10, 2021; Published: August 30, 2022  Show citation