Neurol. praxi. 2022;23(6):499-502 | DOI: 10.36290/neu.2022.002

Cerebellar mutism - a case report

MUDr. Lenka Pospíšilová, prof. MUDr. Martin Vališ, Ph.D., FEAN
Neurologická klinika Fakultní nemocnice v Hradci Králové

Cerebellar mutism is a postoperative complication after an intervention in posterior cranial fossa. It can particularly be seen in children following tumor resection of cerebellar vermis. Clinical features of this syndrome are well described in foreign literature while its pathophysiology stays unclear. The goal of our case report is to point this interesting phenomenon out mainly because it is only sporadicly mentioned in Czech neurological publications.

Keywords: cerebellar mutism, posterior fossa, medulloblastoma.

Received: October 7, 2021; Revised: January 31, 2022; Accepted: February 1, 2022; Prepublished online: February 1, 2022; Published: December 2, 2022  Show citation

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Pospíšilová L, Vališ M. Cerebellar mutism - a case report. Neurol. praxi. 2022;23(6):499-502. doi: 10.36290/neu.2022.002.
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    References

    1. Ackermann H, Mathiak K, Riecker A. The contribution of the cerebellum to speech production and speech perception: clinical and functional imaging data. Cerebellum. 2007;6(3):202-13. Go to original source... Go to PubMed...
    2. Bailey H, Buchanan B, Bucy P. Intracranial tumors of infancy and childhood. Chicago, IL: University of Chicago Press; 1939. Go to original source...
    3. Bolceková E, Mojzeš M, Van Tran Q, et al. Cognitive impairment in cerebellar lesions: a logit model based on neuropsychological testing. Cerebellum Ataxias. 2017;28(4):13. Go to original source... Go to PubMed...
    4. Cobourn K, Marayati F, Tsering D, et al. Cerebellar mutism syndrome: current approaches to minimize risk for CMS. Childs Nerv Syst. 2020;36(6):1171-1179. Go to original source... Go to PubMed...
    5. Gora NK, Gupta A, Sinha VD. Cerebellar mutism syndrome following midline posterior fossa tumor resection in children: an institutional experience. J Pediatr Neurosci. 2017;12(4):313-319. Go to original source... Go to PubMed...
    6. Gudrunardottir T, Sehested A, Juhler M, Schmiegelow K. Cerebellar mutism: review of the literature. Childs Nerv Syst. 2011;27(3):355-63. Go to original source... Go to PubMed...
    7. Jabarkheel R, Amayiri N, Yecies D, et al. Molecular correlates of cerebellar mutism syndrome in medulloblastoma. Neuro Oncol. 2020;22(2):290-297.
    8. Korah MP, Esiashvili N, Mazewski CM, et al. Incidence, risks, and sequelae of posterior fossa syndrome in pediatric medulloblastoma. Int J Radiat Oncol Biol Phys. 2010;77(1):106-12. Go to original source... Go to PubMed...
    9. Lanier JC, Abrams AN. Posterior fossa syndrome: review of the behavioral and emotional aspects in pediatric cancer patients. Cancer. 2017;123:551-559. Go to original source... Go to PubMed...
    10. Law N, Greenberg M, Bouffet E, et al. Clinical and neuroanatomical predictors of cerebellar mutism syndrome. Neuro Oncol. 2012;14(10):1294-303. Go to original source... Go to PubMed...
    11. Paquier PF, Walsh KS, Docking KM, et al. Post­‑operative cerebellar mutism syndrome: rehabilitation issues. Childs Nerv Syst. 2020;36(6):1215-1222. Go to original source... Go to PubMed...
    12. Pols SYCV, van Veelen MLC, Aarsen, FK, et al. Risk factors for development of postoperative cerebellar mutism syndrome in children after medulloblastoma surgery. Journal of Neurosurgery: Pediatrics PED. 2017;20(1):35-41. Go to original source... Go to PubMed...
    13. Reed­‑Berendt R, Phillips B, Picton S, et al. Cause and outcome of cerebellar mutism: evidence from a systematic review. Childs Nerv Syst. 2014;30(3):375-85. Go to original source... Go to PubMed...
    14. Rekate HL, Grubb RL, Aram DM. Muteness of cerebellar origin. Arch Neurol. 1985;42(7):697-698. Go to original source... Go to PubMed...
    15. Renne B, Radic J, Agrawal D, et al. Cerebellar mutism after posterior fossa tumor resection in children: a multicenter international retrospective study to determine possible modifiable factors. Childs Nerv Syst. 2020;36(6):1159-1169. Go to original source... Go to PubMed...
    16. Shyu C, Burke K, Souweidane MM, et al. Novel use of zolpidem in cerebellar mutism syndrome. J Pediatr Hematol Oncol. 2011;33(2):148-9. Go to original source... Go to PubMed...
    17. Tamburrini G, Frassanito P, Chieffo D, et al. Cerebellar mutism. Childs Nerv Syst. 2015;31(10):1841-51. Go to original source... Go to PubMed...
    18. Toescu SM, Hettige S, Phipps K, et al. Post­‑operative paediatric cerebellar mutism syndrome: time to move beyond structural MRI. Childs Nerv Syst. 2018;34(11):2249-2257. Go to original source... Go to PubMed...
    19. Wibroe M, Cappelen, J, Castor C, et al. Cerebellar mutism syndrome in children with brain tumours of the posterior fossa. BMC Cancer. 2017;17:439. Go to original source... Go to PubMed...
    20. Wibroe M, Rochat P, Juhler M. Cerebellar mutism syndrome and other complications after surgery in the posterior fossa in adults: a prospective study. World Neurosurg. 2018;110:e738-e746. Go to original source... Go to PubMed...

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