Neurol. praxi. 2023;24(2):103-110 | DOI: 10.36290/neu.2022.070

Value of OCT­‑A in patients with multiple sclerosis

MUDr. Miriama Skirková, PhD.1, MUDr. Monika Moravská1, MUDr. Marek Horňák1, MUDr. Jozef Szilasi1, doc. MUDr. Jarmila Szilasiová, PhD.2
1 Očná klinika UPJŠ LF a UNLP Košice
2 Neurologická klinika UPJŠ LF a UNLP Košice

Optical coherence tomography angiography (OCT-A) is a novel, non-invasive, fast, repeatable, 3D imaging method for retinal, choroidal, and optic nerve vessels. OCT-A has the potential to become a new biomarker of various ophthalmological (e.g. glaucoma, diabetic retinopathy, age-related macular degeneration) and neurological disorders. Retinal microcirculation share similar features with cerebral small blood vessels, thus OCT-A may be considered a "window" for the detection of microvascular changes which are associated with neurodegenerative disorders, such as multiple sclerosis. In this review, we summarize recent findings regarding the utility of OCT-A as a novel, prospective biomarker for early diagnosis and monitoring of multiple sclerosis.

Keywords: multiple sclerosis, OCT-A, vessel density, ganglion cell layer, retinal nerve fiber layer.

Received: November 7, 2022; Revised: November 7, 2022; Accepted: November 7, 2022; Prepublished online: November 7, 2022; Published: April 21, 2023  Show citation

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Skirková M, Moravská M, Horňák M, Szilasi J, Szilasiová J. Value of OCT­‑A in patients with multiple sclerosis. Neurol. praxi. 2023;24(2):103-110. doi: 10.36290/neu.2022.070.
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