Neurol. praxi. 2010;11(1):16-19

Management of advanced dementia - palliative approach

MUDr.Robert Rusina1, MUDr.MgA.Kateřina Rusinová2, doc.MUDr.Iva Holmerová, Ph.D.3, doc.MUDr.Jiří Šimek, CSc.4
1 Neurologická klinika IPVZ a Fakultní Thomayerovy nemocnice, Praha
2 Klinika anesteziologie, resuscitace a intenzivní medicíny, Všeobecná fakultní nemocnice a 1. LF UK, Praha
3 Gerontologické centrum a Katedra řízení a supervize v sociálních a zdravotnických organizacích, UK FHS, Praha
4 Katedra filozofie a etiky v pomáhajících profesích, Zdravotně sociální fakulta JU v Českých Budějovicích

End-stage of dementia can be defined as a period when the disease reaches irreversible and severely reduced autonomy in basic activities

of daily living with a need of persistent nursing care. Treatment options, mainly acetylcholinesterase inhibitors and memantin,

decision making capacity and principles of autonomy in these patients are discussed. Indication of intensive care, the role of palliative

approaches and management of complications are described. Finally, the importance of communication with the patient and the caregiver

and aspects of institutionalization are mentioned more in detail.

Keywords: dementia, end stage disease, prognosis, intensive care, palliative care

Published: March 1, 2010  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Rusina R, Rusinová K, Holmerová I, Šimek J. Management of advanced dementia - palliative approach. Neurol. praxi. 2010;11(1):16-19.
Download citation

References

  1. Carlet J, Thijs LG, Antonelli M, Cassell J, Cox P, Hill N, Hinds C, Pimentel JM, Reinhart K, Thompson BT. Challenges in end-oflife care in the ICU Statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003. Intensive Care Med 2004; 30: 770-784. (www.srlf.org/Data/ ModuleGestionDeContenu/application/577.pdf). Go to original source... Go to PubMed...
  2. Černý V (editor). Konsensuální stanovisko k poskytování paliativní péče u nemocných s nezvratným orgánovým selháním Česká společnost anesteziologie, resuscitace a intenzivní medicíny ČLS JEP, Česká společnost intenzivní medicíny ČLS JEP 2009 (http://www.csim.cz/Cz/News.aspx).
  3. Davidson JE, Powers K, Hedayat KM, Tieszen M, Kon AA, Shepard E, Spuhler V, Todres ID, Levy M, Barr J, Ghandi R, Hirsch G, Armstrong D. Clinical practice guidelines for support of the family in the patient-centered intensive care unit: American College of Critical Care Medicine Task Force 2004-2005. Crit Care Med 2007; 35: 605-622. Go to original source... Go to PubMed...
  4. Gove D, Sparr S, Dos Santos Bernardo AMC, Cosgrave MP, Jansen S, Martensson B, Pointon B, Tudose C, Holmerová I. Recommendations on end-of-life care for people with dementia. J Nutr Health Aging 2009 (in press). Go to original source... Go to PubMed...
  5. Herrmann N, Gauthier S. Diagnosis and treatment of dementia: 6. Management of severe Alzheimer disease. CMAJ 2008; 179: 1279-1287. (http://www.cmaj.ca/cgi/content/full/179/12/1279). Go to original source... Go to PubMed...
  6. Holmerová I, Vaňková H, Baumanová M, Jurašková B. Bolest - podceněný problém v péči o pacienty s demencí, Česká geriatrická revue, 2009; 7(1): 31-35.
  7. Hughes JC, Robinson J, Volicer L. Specialist palliative care in dementia, BMJ 2005; 330: 57-58. Go to original source... Go to PubMed...
  8. Mitchell SL, Teno JM, Kiely DK, Shaffer ML, Jones RN. Prigerson HG, Volicer L, Givens JL, Hamel MB. The Clinical Course of Advanced Dementia, N Engl J Med 2009; 361(16): 1529-1538. Go to original source... Go to PubMed...
  9. National Institute for Clinical Excellence: Dementia: Supporting people with dementia and their carers in health and social care. NICE guidelines 2006. (http://guidance.nice.org.uk/CG42).
  10. Sheardová K, Hort J, Rusina R, Bartoš A, Línek V, Ressner P, Rektorová I. Doporučené postupy pro léčbu Alzheimerovy nemoci a dalších onemocnění spojených s demencí. Cesk Slov Neurol N 2007; 70(103): 589-594. http://www.csnn.eu/dpplan.pdf.
  11. Shega JW, Ellner L, Lau DT, Maxwell TL. Cholinesterase inhibitor and N-methyl-D-aspartic acid receptor antagonist use in older adults with end-stage dementia: a survey of hospice medical directors. J Palliat Med 2009; 12: 779-783. Go to original source... Go to PubMed...
  12. Volicer L, Hurley A. Hospice Care for Patients with Advanced Progressive Dementia, Springer Series on Ethics, Law and Aging, New York, 1998.
  13. Waldemar G, Dubois B, Emre M, Georges J, McKeith IG, Rossor M, Scheltens P, Tariska P, Winblad B. Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline. Eur J Neurol 2007; 14: e1-e26. (www.efns.org sekce guidelines). Go to original source... Go to PubMed...
  14. Wang PS, Schneeweiss S, Avorn J, Fischer MA, Mogun H, Solomon DH, Brookhart MA. Risk of death in elderly users of conventional vs atypical antipsychotic medications. New England Journal of Medicine 2005; 353: 2335-2341. Go to original source... Go to PubMed...




Neurology for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.