Neurol. praxi. 2018;19(3):183-186 | DOI: 10.36290/neu.2018.094

Focal forms of acute polyradiculoneuritis

doc. MUDr. Edvard Ehler, CSc.

Neurologická klinicka FZS Univerzita Pardubice, Pardubická krajská nemocnice, Pardubice

Acute polyradiculoneuritis (Guillain-Barré syndrome – GBS) is a multifocal autoimmune form of neuropathy. This neuropathy has its classicalforms – acute inflammatory demyelinating polyradiculoneuritis (AIDP) affects myelin sheath and primary axonal form is characterizedby pure motor disorder AMAN or severe mixed sensory-motor form AMSAN. Among the variants or focal forms can be differentiatedMiller-Fisher syndrome with clinical trias – ophthalmoplegia, ataxia and areflexia – and pharyngo-cervico-brachial form with dysphagia,weakness of neck and brachial muscles. Besides these two most frequent variants there some other forms – Bickerstaff brainstemencephalitis, paraparetic form of GBS (Guillain-Barré syndrome), cranial neuropathies, acute pandysautonomia, pure sensory form ofGBS. The individual variants are charactrized by clinical symptoms, the course, by abnormal neurophysiological investigations, therapy.

Keywords: acute polyradiculoneuritis, autoimmune inflammation, electromyography, immunological therapy

Published: July 1, 2018  Show citation