Slovo úvodem

prof. MUDr. Ivan Rektor, CSc.

Neurol. praxi. 2012;13(1):3  

Bolesti hlavy - úvod k hlavnímu tématu

doc. MUDr. Otakar Keller, CSc. - editor hlavního tématu

Neurol. praxi. 2012;13(1):6  

Endocrinally influenced headaches

MUDr.Ingrid Niedermayerová

Neurol. praxi. 2012;13(1):7-9  

Migraine is a typical disease with a significant influence of women sex hormones. In trigeminal autonomic cephalgias is activated hypothalamus during attacks. Migrainelike headache is the most common presentation of pituitary adenomas, clusterlike headache is less often. Pituitary apoplexy is manifested by thunderclap headache. Headache is presented in 30 % patient with hypothyroidism. Paroxysmal headache occur in 50–80 % patients with phaeochromocytoma. Migraines with aura in females is more likely to worsen due to combined oral hormonal contraception and are higher at risk of migraine stroke, especially with those who smoke. Administration...

Persistent migraine aura without infarction

MUDr.Jiří Mastík

Neurol. praxi. 2012;13(1):10-13  

Persistent aura without infarction (PAWI) is among rare complications of migraine. The diagnostic criteria include: a history of attacks of migraine with aura; an aura persisting for more than one week; and a neuroradiological examination failing to demonstrate migrainous infarction. The most common symptoms of aura are visual and may persist for months or years. The differential diagnostic process involves ruling out complications of migraine (migrainous infarction, status migrainous) as well as some eye diseases (such as vitreous opacities), visual hallucinations in psychiatric diseases, hallucinogen persisting perception disorders and some...

Mediaction overuse headache

MUDr.Jolana Marková

Neurol. praxi. 2012;13(1):14-16  

Medication overuse headache belongs to the group of chronic daily headache (CDH). When some of the serious secondary headaches, such as brain tumour, cerebrovascular disease or other diseases caused by a structural lesion of the central nervous system, are ruled out, in typical migraine sufferers CDH may develop by transformation from episodic to chronic migraine, or it may be primary chronic tension- type headache, and/or the headache may result from overuse of medications (medication overuse headache, MOH). In the latter case, there is primarily an interaction between an excessively used acute analgesic drug and a predisposed type of patient....

Painful diabetic neuropathy

prof.MUDr.Zdeněk Ambler, DrSc.

Neurol. praxi. 2012;13(1):17-20  

Painful diabetic neuropathy is common and is associated with significant reduction in quality of life. A distal and symmetric peripheral neuropathy is the most frequent form, and small fiber damage is thought to result in painful symptoms. The much less common though well recognized are acute painful and atypical neuropathies. Management of the patient with painful neuropathy is difficult, must be tailored to individual requirements, taking into consideration comorbidities and other factors. Pharmacological management represents the most important therapeutic option for chronic neuropathic pain. Current first-line agents with proven efficacy...

Neuromuscular disorders in thyroid disease

MUDr.Radim Mazanec, Ph.D., MUDr.Tomáš Nedělka, doc.MUDr.Martin Bojar, CSc.

Neurol. praxi. 2012;13(1):22-25  

Thyroid gland dysfunction is beside diabetes mellitus the most common endocrinopathy. Both hypothyroidism and hyperthyroidism may cause signs and symptoms of neuromuscular dysfunction. Hypothyroidism is associated with clinical neuromuscular features in 79 % and hyperthyroidism in 67 % patients. Proximal myopathy, sensorimotor axonal neuropathy and carpal tunnel syndrome are the most common disorders in hypothyroidism. Hyperthyroidism (Graves Basedow disease) may cause hyperthyroid myopathy, thyrotoxic periodic paralysis and thyroid-associated ophtalmopathy. Peripheral sensorimotor neuropathy is rare. Neuromuscular symptoms and signs usually...

Alzheimer, s disease and mixed dementia - one entity or two?

MUDr.Stanislav Šutovský, PhD., MUDr.Mária Králová, PhD., MUDr.Ľubomíra Izáková, PhD., prof.MUDr.Peter Turčáni, PhD.

Neurol. praxi. 2012;13(1):26-31  

Mixed dementia refers to a combination of neurodegenerative and cerebrovascular process with a presumption of an equal contribution of both pathologies on the cognitive deficit. Neurodegenerative and cerebrovascular pathology increases in an aging brain and that can present clinically in a different extent. In our work we summarize clinical and pathological interactions between both pathologies. We try to determine the borders of mixed dementia and in accordance with data available so far we analyse mixed dementia anticipated prevalence and summarise diagnostic criteria and clinical characteristics.

Two-centimetre segment study of ulnar nerve motor conduction across the elbow - electromyographic technique

MUDr.Eduard Minks, MUDr.Ivica Husárová, Anna Hlučková, MUDr.Hana Streitová, Mgr.Lumír Konečný, Ph.D., Mgr.Jaroslava Pochmonová, Ph.D., prof.MUDr.Martin Bareš, Ph.D.

Neurol. praxi. 2012;13(1):32-37  

Neuropathy of the ulnar nerve at the elbow is only second to carpal tunnel syndrome as the most common cause of upper extremity mononeuropathies encountered by an outpatient neurologist and an electromyographer in their practice. In clinical electromyography, a number of motor and sensory conduction studies and needle electromyography are used to diagnose this mononeuropathy. Segment study of motor conduction across the elbow (inching) is a less-commonly used technique due to the demands for execution and interpretation. However, this examination is essential because of accurate localization of the injury and may be beneficial in the case of...

Vegetative state in relation to instrumental methods of investigation

Mgr.Lucie Augustini, MUDr.Tomáš Gabrhelík, Ph.D.

Neurol. praxi. 2012;13(1):38-43  

Instrumental methods of investigation, such as positron emission tomography, functional magnetic resonance imaging, electroencephalography and evoked potential measurement, yield a lot of information useful for differential diagnosis and for determining the prognosis of patients in a vegetative state. Consequently, they also allow for a better understanding of how the brain of a patient in a vegetative state works.

Spontaneous epidural hematoma in the cervical spine

MUDr.Lubomír Jurák, MUDr.Pavel Buchvald, MUDr.Radim Brabec, doc.MUDr.Petr Suchomel, Ph.D.

Neurol. praxi. 2012;13(1):44-46  

Spontaneous spinal epidural hematoma is a rare clinical entity. It represents less than 1 % of all lesions located in the epidural space of the spinal canal. Our case report describes 63-year-old patient admitted for a suddenly incurred intense neck pain and paresthesia in the right upper limb with progression to severe right spasic hemiparesis. The magnetic resonance showed epidurally located mass in the area C3–4, dorsal to the spinal cord with its significant compression. We urgently evacuated the expansion. No possible cause of hematoma was discovered during the surgery and the histopathological exam disclosed only parts of hematoma....

Subcortical band heterotopia of the cerebral cortex with pharmacoresistant epilepsy

MUDr.Milan Labonek, MUDr.Marta Neklanová, MUDr.Jindřiška Burešová, doc.MUDr.Stanislav Buřval, Ph.D., doc.MUDr.Robert Kuba, Ph.D., prof.MUDr.Roman Herzig, Ph.D., prof.MUDr.Petr Kaňovský, CSc.

Neurol. praxi. 2012;13(1):47-52  

Subcortical laminar heterotopia of the cerebral cortex, also referred to as band heterotopia (BH) or double cortex, is a rather rare developmental defect of the cerebral cortex characterized by the presence of large bands of grey matter below the surface of the cortex. This malformation occurs mostly in women and is manifested as sporadic or familial cases with epilepsy and varying degrees of mental retardation. The most common cause of the disease is a mutation in the doublecortin gene, resulting in BH in females and, predominantly, in agyria-pachygyria and, only sporadically, in BH in males. Two female patients were followed for delayed psychomotor...

Publikujeme v zahraničí

Neurol. praxi. 2012;13(1):58  

Neurologové se ptají …

prof. MUDr. Roman Herzig, Ph.D., FESO

Neurol. praxi. 2012;13(1):57  

Author‘s view to beginning period of stimulation therapy of epilepsy and its signification

prof.MUDr.Pavel Nádvorník, DrSc., MUDr.Viera Drličková, CSc.

Neurol. praxi. 2012;13(1):53-55  

The concise overview of the results of dentate nucleus, caudate nucleus and direct epileptogenic focus stimulation provides historical evidence about the first – time use of stereotactic techniques and externalised electrodes in epilepsy patiens in standard fashion. At the same time the technique have provided the possibility to think of the role of memory in epileptogenesis and also of the new treatment approaches for epilepsy patients.

Konference Multidisciplinární péče o pacienty s nervosvalovými onemocněními se zvláštním zřetelem na spinální muskulární atrofii (SMA)

Helena Kočová

Neurol. praxi. 2012;13(1):56  

Ocenění od vydavatelství časopisu Lancet Neurology

MUDr. Petra Bártová, Ph.D.

Neurol. praxi. 2012;13(1):56